An Atypical Presentation of Multiple Sclerosis

Abstract

Multiple Sclerosis (MS) involves an immune mediated process in which an abnormal response of the body's immune system is directed against the central nervous system (CNS). Multiple sclerosis is a very variable condition and the symptoms depend on which areas of the CNS have been affected. There is no set pattern for MS and everyone with MS has a different set of symptoms, which vary from time to time and can change in severity and duration, even in the same person. Hence diagnosing MS at the earliest is very essential. Therefore we report an unusual case of a 30-yearold female with complaints of headache, vomiting & hiccups since 2 months followed by weakness of bilateral lower limbs and later upper limbs which eventually were diagnosed as Multiple Sclerosis. We are reporting this case because of the vague clinical presentation of Multiple Sclerosis. Aim: To recognize the symptoms of MS at the earliest and start treatment early.

Single Test to ARrive at Multiple Sclerosis (STAR-MS) diagnosis: A prospective pilot study assessing the accuracy of the central vein sign in predicting multiple sclerosis in cases of diagnostic uncertainty

“…However, a significant proportion of patients referred to MS clinics have an atypical history, examination or MR findings, leading to delays in diagnosis or misdiagnosis. 19 Offering the diagnosis of MS depends not only on the clinical presentation and MRI findings but on the clinician’s interpretation, experience and diagnostic confidence. For example, many of the patients who were ultimately clinically diagnosed with non-MS conditions had evidence of dissemination in space (DIS) at presentation, increasing their chances of a misdiagnosis.…”