An atypical presentation of tuberculosis of the spine

Pande, Ketan C; Pande, Sonali; Babhulkar, SS

doi:10.1038/sc.1996.130

Cited by 14 publications

(15 citation statements)

References 10 publications

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“…Our findings are in agreement with those of Pande et al. who reported that in 87 patients with ‘failed back syndrome’, 12 were confirmed to have tuberculous discitis [20]. Galukande et al.…”

Section: Discussionsupporting

confidence: 94%

“…The findings of this study indicate that TB is a common cause of LBP in our population. Our findings are in agreement with those of Pande et al who reported that in 87 patients with 'failed back syndrome', 12 were confirmed to have tuberculous discitis [20]. Galukande et al also reported that in patients with LBP, a significant percentage had spinal pathology caused by tuberculosis [21].…”

Section: Discussionsupporting

confidence: 93%

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Spinal tuberculosis: overlooked?

Abou‐Raya

2006

Journal of Internal Medicine

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Objective. The aim of the present study was to ascertain the degree of occurrence of tuberculous infection in patients presenting with low back pain (LBP). Methods. Forty consecutive patients seeking primary medical attention for the main symptom of LBP and presenting to the Rheumatology Outpatient Clinic of our institution from January 2004 to June 2005, were recruited in this cohort study. All patients were thoroughly interrogated (occupational, trauma, infection, diabetes mellitus and medication history), subjected to a rigorous clinical examination and a battery of investigations Results. Twelve of the 40 patients (33%) proved to have spinal TB as the cause of backache. Eight of these patients were above the age of 65. Five of the 12 patients with spinal TB also had concomitant osteoarthritic changes of the spine and two patients had concomitant disc prolapse. Eleven of the 12 patients with spinal TB had a completely normal chest X-ray and in 10 of these patients the plain X-ray of the lumbosacral region failed to show any significant lesion. In all 12 patients, sputum analysis failed to reveal acid-fast bacilli. Conclusions. The findings of this study indicate that TB is a common cause of LBP that is liable to be overlooked in the differential diagnosis of LBP. Furthermore, evidence of concurrent active intrathoracic TB may be lacking and consequently a high level of suspicion is required. The need for prompt diagnosis and treatment of skeletal TB is of utmost importance to prevent serious bone and joint destruction and severe neurological sequelae. A reliable imaging modality for diagnosing spinal TB seems to be magnetic resonance imaging.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 93%

Spinal tuberculosis: overlooked?

Abou‐Raya

2006

Journal of Internal Medicine

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“…Atypical features that were described in the previous reports are 1) involvement of the spinal posterior element with a sparing of the anterior column; 2) skip lesions; and 3) neural component compression as a result of tuberculosis granuloma4. The most common site of involvement of the posterior element of the spine is the pedicle1.…”

Section: Discussionmentioning

confidence: 93%

Tuberculosis of the Lower Lumbar Spine with an Atypical Radiological Presentation - A Case Mimicking a Malignancy -

2007

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A 65-year-old woman was treated for an atypical radiological presentation of spinal tuberculosis. Compared with previously reported cases, the following two different radiographic features were found. 1) Although there was multiple and skipped involvement of the vertebral body, the intervertebral disc was relatively preserved. 2) The presence of an epidural granuloma indicated an epidural extension of the lesion of the adjacent vertebral body. These findings strongly mimicked bone marrow infiltrative disease such as a malignancy. Tuberculosis was confirmed through an open biopsy and the patient was treated successfully with antitubercular chemotherapy. This case highlights the importance of being aware that spinal tuberculosis has many different radiographic features and can mimic a spinal malignancy.

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“…S pinal tuberculosis in its classical form (i.e., two-vertebra disease with destruction of the intervening intervertebral disk and a paravertebral or psoas abscess) is easily recognized and readily treated in areas where tuberculosis is endemic [1][2][3][4] . Atypical spinal tuberculosis without the aforementioned clinical or radiographic features 5 , although occurring less frequently 6 , has been well documented [6][7][8] . However, only a few articles have reported isolated tuberculosis involving a single vertebral body 1,9,10 .…”

Section: Introductionmentioning

confidence: 99%

“…However, only a few articles have reported isolated tuberculosis involving a single vertebral body 1,9,10 . Single vertebra tuberculosis presenting with a localized, solitary, osteolytic lesion without collapse of vertebral body is exceedingly rare and there is limited information about this entity in English-language published reports 1,2,[5][6][7][8][9][10] .…”

Section: Introductionmentioning

confidence: 99%

Single Vertebra Tuberculosis Presenting with Solitary Localized Osteolytic Lesion in Young Adult Lumbar Spines

Peng

Liu

Lü

2013

Orthopaedic Surgery

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Tuberculosis affecting a single vertebral body presenting with a localized solitary osteolytic lesion is an unusual form of single vertebra tuberculosis. MRI combined with CT scan of the vertebral body can be very helpful for precisely defining the location of the lesion and extent of osseous destruction. Such small, solitary, osteolytic lesions are often confused with other single vertebra diseases that can have similar appearances on imaging.

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An atypical presentation of tuberculosis of the spine

Cited by 14 publications

References 10 publications

Spinal tuberculosis: overlooked?

Spinal tuberculosis: overlooked?

Tuberculosis of the Lower Lumbar Spine with an Atypical Radiological Presentation - A Case Mimicking a Malignancy -

Single Vertebra Tuberculosis Presenting with Solitary Localized Osteolytic Lesion in Young Adult Lumbar Spines

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