An atypical Ramsey Hunt syndrome after covid 19 immunization

Lakhoua, Ghozlane; Charfi, Ons; Dabbehce, Sana; Zaiem, Ahmed; Kastalli, Sarrah; Daghfous, Riadh; Aidli, Sihem El

doi:10.1016/j.therap.2022.07.005

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…Finally, Lakhoua et al reported a 65-year-old who was presented with RHS seven days after BNT162b2 mRNA vaccination. He was treated with valacyclovir and pregabalin with improvement in lesions but he was still complaining of post-herpetic neuralgia at six-month follow-up (24). To the best of our knowledge, our case is the rst describing RHS following Sinopharm vaccination in a healthy young man.…”

Section: Discussionmentioning

confidence: 77%

Ramsay-Hunt-Syndrome Associated with Unilateral Parotitis Following COVID-19 Vaccine

Soltanipur,

Yarmohammadi,

Anari

et al. 2024

Preprint

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Varicella-zoster-virus (VZV) reactivation is a recognized complication following COVID-19 vaccination; however, Ramsey-hunt-syndrome (RHS) rarely has been reported. This case presents a 36-year-old immunocompetent man with features of RHS three weeks following the second dose of the BBIBP-CorV (Sinopharm) vaccine. Interestingly, he developed acute unilateral parotitis on his left side and the ultrasonography showed a 55*44*18 mm parotid gland with decreased parenchymal echogenicity. He was treated with valacyclovir, and after seven days he was discharged. Also, his parotitis was resolved by day 29 following the presentation of the first symptoms with no further complications. The possibility of VZV reactivation after COVID-19 vaccination is an important point and it should be noted that this reactivation might present in unusual clinical scenarios.

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Section: Discussionmentioning

confidence: 77%

Ramsay-Hunt-Syndrome Associated with Unilateral Parotitis Following COVID-19 Vaccine

Soltanipur,

Yarmohammadi,

Anari

et al. 2024

Preprint

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“…Ramsay Hunt syndrome, which is linked to VZV infection, is another area of concern. A possible connection between SARS-CoV-2 infection or COVID-19 vaccination and Ramsay Hunt syndrome has been suggested in several case reports 36 37 38 39 Ramsay Hunt syndrome, accompanied by VZV meningitis following COVID-19 vaccination or post-SARS-CoV-2 infection was reported, which is extremely rare in immunocompetent individuals, and the authors suggested that viral activation of the facial nerve during the convalescent phase of COVID-19 or vaccination status might cause perturbations in immunity. While our data did not show significant Ramsay Hunt syndrome changes pre- and after the COVID-19 pandemic, understanding this relationship requires extensive epidemiological research.…”

Section: Discussionmentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on Bell’s Palsy and Ramsay-Hunt Syndrome: A Multicenter Retrospective Study

Kwak,

Lee,

Lee

et al. 2024

J Korean Med Sci

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Background This article presents a comprehensive review of data on the impact of facial palsy during the coronavirus disease 2019 (COVID-19) pandemic. The possible causes and pathophysiological mechanisms of changes in the epidemiology of facial palsy during the COVID-19 pandemic are also discussed. Methods This multicenter retrospective cohort study included 943 patients diagnosed with Bell’s palsy or Ramsay Hunt syndrome. This study compared patient demographics, comorbidities, symptoms, and treatments before the COVID-19 pandemic (from 2017 to 2019) and during the COVID-19 pandemic, from 2020 to 2022). Results Following the COVID-19 outbreak, there has been a significant increase in the number of cases of Bell’s palsy, particularly among elderly individuals with diabetes. Bell’s palsy increased after the COVID-19 outbreak, rising from 75.3% in the pre-COVID-19 era to 83.6% after the COVID-19 outbreak. The complete recovery rate decreased from 88.2% to 73.9%, and the rate of recurrence increased from 2.9% to 7.5% in patients with Bell’s palsy. Ramsay Hunt syndrome showed fewer changes in clinical outcomes. Conclusion This study highlights the impact of the COVID-19 pandemic on the presentation and management of facial palsy, and suggests potential associations with COVID-19. Notably, the observed increase in Bell’s palsy cases among elderly individuals with diabetes emphasizes the impact of the pandemic. Identifying the epidemiological changes in facial palsy during the COVID-19 pandemic has important implications for assessing its etiology and pathological mechanisms of facial palsy disease.

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“…PubMed research looking for articles published at any time till October 2023 in the English language and combining the words "COVID-19" OR "SARS-CoV-2" AND "Ramsay Hunt Syndrome" OR "herpes zoster oticus" has identified five cases of RHS in the context of COVID-19 infection [1,[11][12][13][14] and three cases of RHS following COVID-19 vaccination [15][16][17]. A summary of the case reports is available in Tables 1 and 2.…”

Section: Available Case Reports Of Ramsay Hunt Syndrome In the Contex...mentioning

confidence: 99%

“…To the best of our knowledge, only a few reports have described RHS in association with COVID-19 infection [1,[11][12][13][14] or 2-3 days after administration of the COVID-19 vaccine [15][16][17]. Setting the right diagnosis allows the delivery of proper management and optimization of the clinical recovery.…”

Section: Introductionmentioning

confidence: 99%

Ramsay Hunt Syndrome in Asymptomatic COVID-19 Infection: A Case Report and a Literature Review

Ayoub,

Lizzeik,

Berro

et al. 2023

JCM

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(1) Background: COVID-19 infection has affected almost 6 million people worldwide. Geniculate Ganglion Zoster resulting in Ramsay Hunt Syndrome (RHS) has been rarely described in this context. (2) Methods: Here, a case of RHS in the context of asymptomatic COVID-19 infection is reported followed by a literature review of the previously published cases (PubMed research combining “COVID-19” and “Ramsay Hunt Syndrome” or their abbreviations/synonyms, searching for data published at any time till October 2023). (3) Results: Five cases have been previously published (age range: 25–67 years; n = 3 males). Three patients were known to be immunocompetent prior to infection, one was receiving corticotherapy for lung disease, and one had an unspecified immune status. RHS predominantly involved both facial and vestibulocochlear nerves, with one case exclusively involving the facial nerve as the presented case. Regarding facial nerve palsy, three were right-sided (like the current report) and two were left-sided. Two cases were asymptomatic to COVID-19 (like the present patient), one had mild fatigue, and two had classical COVID-19 symptoms preceding RHS symptoms. Workup included serological testing against Varicella Zoster Virus and PCR assays that can detect the viral DNA in saliva, blood, tears, exudates, and cerebrospinal fluid. The treatment combined antiviral and corticosteroid therapies which yielded heterogeneous outcomes that might be related to some demographic and clinical data. (4) Conclusions: RHS rarely occurs in the context of COVID-19. Early recognition is important. Management seems to be similar to the classical condition. Some data may help predict facial nerve recovery.

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An atypical Ramsey Hunt syndrome after covid 19 immunization

Cited by 4 publications

References 8 publications

Ramsay-Hunt-Syndrome Associated with Unilateral Parotitis Following COVID-19 Vaccine

Ramsay-Hunt-Syndrome Associated with Unilateral Parotitis Following COVID-19 Vaccine

The Impact of the COVID-19 Pandemic on Bell’s Palsy and Ramsay-Hunt Syndrome: A Multicenter Retrospective Study

Ramsay Hunt Syndrome in Asymptomatic COVID-19 Infection: A Case Report and a Literature Review

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