An audit of fifty patients receiving Artiss™ fibrin sealant in lateral selective neck dissections

Earnshaw, Charles H.; Kinshuck, Andrew; Loh, Christopher; Tandon, Sankalap; Jackson, Sarah; Jones, Terry M.; Lancaster, Jeffrey

doi:10.1111/coa.13485

Cited by 3 publications

(5 citation statements)

References 9 publications

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“…This preliminary study has shown that Artiss™ can be a safe alternative to the use of surgical drains in LNDs, reducing complications and allowing for discharge on the same day of surgery. This aligns with previously published retrospective data on LNDs and superficial parotidectomies 9–11 …”

Section: Discussionsupporting

confidence: 91%

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Drainless, day‐case lateral neck dissection with Artiss™ fibrin sealant: A prospective cohort study

Tabaksert,

James,

Rusius

et al. 2024

Head & Neck

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ObjectiveLateral neck dissection (LND) is performed for staging/treatment of head and neck lesions. This traditionally includes placement of a drain and inpatient admission. Drainless, day‐case head and neck surgery is attractive due to cost‐effectiveness and reduced length of stay, but evidence is lacking in LND. We aim to investigate Artiss™ as an alternative to drain placement, facilitating day‐case LND.MethodsA prospective review was conducted of patients who underwent LND in a UK hospital over a 22‐month period.ResultsThirty‐nine patients were identified (27 Artiss™ only; 12 Artiss™ with a drain). Eight Artiss™ only patients were day‐case. All drains were removed by post‐operative day 2. There was no statistically significant difference in the number of complications between the two groups.ConclusionThis observational study demonstrates that for selected patients, Artiss™ could facilitate drainless, day‐case LND. Further controlled studies with matched groups and larger numbers are required to validate this.

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Section: Discussionsupporting

confidence: 91%

“…This aligns with previously published retrospective data on LNDs and superficial parotidectomies. [9][10][11] 8/27 patients (30%) in the Artiss™ only group were discharged the same day. In the overnight stay Artiss™ only group, 13/19 patients were discharged day 1 postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Drainless, day‐case lateral neck dissection with Artiss™ fibrin sealant: A prospective cohort study

Tabaksert,

James,

Rusius

et al. 2024

Head & Neck

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“… 8 In contrast, Mushi et al and Earnshaw et al reported decreased drain output, length of drain placement, and length of hospitalization in retrospective cohort reviews of selective neck dissections. 9 , 10 Of note, the first 2 studies were significantly underpowered (8 and 15 patients in the intervention groups, respectively), and all 3 reports did not account for a variety of patient, disease, and surgical factors. Without controlling for such elements, the latter 2 reports inappropriately conclude that fibrin sealant spray and tissue adhesives dramatically reduce length of hospitalization.…”

Section: Discussionmentioning

confidence: 99%

“…In a prospective analysis, Huang et al demonstrated no significant differences in drainage amount and duration of drain placement with fibrin sealant use 8 . In contrast, Mushi et al and Earnshaw et al reported decreased drain output, length of drain placement, and length of hospitalization in retrospective cohort reviews of selective neck dissections 9,10 . Of note, the first 2 studies were significantly underpowered (8 and 15 patients in the intervention groups, respectively), and all 3 reports did not account for a variety of patient, disease, and surgical factors.…”

Section: Discussionmentioning

confidence: 99%

Outcomes Associated With Fibrin Sealant Use in Lateral Neck Dissections

et al. 2020

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Objective To determine whether the use of fibrin sealant tissue adhesives during lateral neck dissections is associated with a change in postoperative outcomes. Study Design Retrospective cohort. Setting Institutionally affiliated tertiary care center. Methods Various demographic, disease, and surgical data were collected for patients who underwent lateral neck dissections. Univariate regression analysis was performed with the following outcomes: total drain output and duration of drain placement, as well as incidence of postoperative infection, hematoma, seroma, chyle leak, and salivary leak. Results A total of 133 patients underwent lateral neck dissections. Fibrin sealant was used in 35% of cases (n = 46). Its use was not associated with differences in total drain output ( P = .77) or the number of days that the drains were in place ( P = .83). On secondary analysis, the use of fibrin sealant was not associated with a difference in postoperative incidence of hematoma ( P = .65), seroma ( P = .68), chyle leak ( P = .42), or salivary leak ( P = .73). These results were consistent when stratified by the presence of intraoperative complications. Its use accompanied an average cost of $674 per case. Conclusions Fibrin sealant use during lateral neck dissections was not associated with a reduction in drain output or days that the drains remained in situ. Although the current study was limited by sample size, fibrin sealant use was not associated with a decreased risk of postoperative adverse events. The evidence in this report suggests that the routine use of these products adds cost without clear benefit.

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“…Earnshaw et al (2020) used ARTISS® in 50 patients undergoing lateral selective neck dissections, showing a significant reduction in the length of the hospital stay of the patients, in the drain retention time, and in the total volume drained. Moreover, they reported an easier use of ARTISS® in comparison to TISSEEL® [ 136 ] ( Table 2 ).…”

Section: Skin Spraysmentioning

confidence: 99%