An audit of surgical repair of Tetralogy of Fallot in an African tertiary care centre

Ngwezi, Deliwe P.; Vanderdonck, K.; Levin, Solomon E.; Cilliers, Antoinette

doi:10.24170/10-3-1792

Cited by 1 publication

(2 citation statements)

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“…In our series, longer and/or repeated runs of cardiopulmonary bypass and longer aortic cross‐clamp time were strongly associated with increased risk of mortality, consistent with the existing literature . A small pulmonary valve annulus, the distal main PA diameter, the left and right branch PA diameters at the origin indexed by BSA and repeated preoperative phlebotomy procedures were associated with an increased risk of perioperative mortality (Table ).…”

Section: Discussionsupporting

confidence: 88%

“…However, in this study, all patients with TOF received palliative shunts, in contrast to our patients, among whom nearly all patients underwent open‐heart surgery with total repair. An audit from a center in South Africa reported outcomes from 54 patients, but again, their center is an established surgical facility, in contrast to ours, which for many years depended on visiting surgical missions from overseas centers.…”

Section: Discussioncontrasting

confidence: 58%

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Factors associated with perioperative mortality in children and adolescents operated for tetralogy of Fallot: A sub‐Saharan experience

et al. 2019

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Background: Patients with tetralogy of Fallot are now surviving to adulthood with timely surgical intervention. However, many patients in low-income countries have no access to surgical intervention. This paper reports the surgical access and perioperative mortality in a sub-Saharan center that was mainly dependent on visiting teams. Methods:We reviewed records of patients operated from January 2009 to December 2014. We examined perioperative outcomes, primarily focusing on factors associated with perioperative mortality.Results: During this period, 62 patients underwent surgery. Fifty-seven (91.9%) underwent primary repair, while 5 (6.5%) underwent palliative shunt surgery. Of the five patients with shunt surgery, four ultimately underwent total repair. Eight (12.9%) patients died during the perioperative period. Factors associated with perioperative mortality include repeated preoperative phlebotomy procedures (P < .001), repeated runs and long cardiopulmonary bypass time (P < .001), and aortic cross-clamp time (P < .001), narrow pulmonary artery (PA) valve annulus diameter (P = .022), narrow

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Section: Discussionsupporting

confidence: 88%

Section: Discussioncontrasting

confidence: 58%