An automatic counter for autoradiographed cells in Petri dishes

Schmialek, Peter; Zapf, Burger; Baisch, F.; Geyer, Astrid; Miosga, Verena; Nündel, M.

doi:10.1111/j.1365-2818.1978.tb00142.x

Cited by 2 publications

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“…In view of the findings cited above, any studies carried out on the binding of radiolabeled samples of 1 with macromolecules (cf. Schmialek et al, 1975) should preferably be carried out with the pure enantiomers of 1. One would expect that only specific binding demonstrable for the biologically active (7S)-(+) enantiomer of 1 would be relevant to the mechanism of action of this juvenile hormone analogue.…”

Section: Dmentioning

confidence: 99%

Insect juvenile hormone activity of optically active alkyl (2E,4E)-3,7,11-trimethyl-2,4-dodecadienoates and of arylterpenoid analogs

Henrick¹,

Anderson²,

Staal³

et al. 1978

J. Agric. Food Chem.

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Optically active samples of a number of alkyl (2E,4E)-3,7,11-trimethyl-2,4-dodecadienoates were prepared and bioassayed (along with the racemic mixtures) for juvenile hormone activity on the yellow-fever mosquito (Aedes aegypti), the greater wax moth (Galleria mellonella), the yellow mealworm (Tenebrio rnolitor), the house fly (Musca dornestica), and the tobacco budworm (Heliothis uirescens). The (S)-(+) enantiomers, in general, showed considerably higher activity on these species than did the (R)-(-) enantiomers. The juvenile hormone activity of the enantiomers of the phenyl ether, 6,7-epoxy-1-(4-ethylphenoxy)-3,7-dimethyloctane and of the arylterpenoid analogue, 8-ethoxy-l-(4-isopropylphenyl)-4,8-dimethylnonane were also studied as examples of different types of juvenile hormone analogues. The differences in activity observed for all of these analogues implies that a chiral receptor system (and possibly more than one such system) is involved in the insect juvenile hormone response to these compounds.The alkyl (2E,4E)-3,7,11-trimethyl-

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Section: Dmentioning

confidence: 99%

Insect juvenile hormone activity of optically active alkyl (2E,4E)-3,7,11-trimethyl-2,4-dodecadienoates and of arylterpenoid analogs

Henrick¹,

Anderson²,

Staal³

et al. 1978

J. Agric. Food Chem.

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The Kinetics of Contact Inhibition in Mammalian Cells

et al. 1977

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To elucidate the process of contact inhibition in mammalian cells, we investigated the kinetics of growth arrest in [3H]thymidine labelled embryonic chinese hamster (Cricetulus griseus L.) cells after the addition of various concentrations of unlabelled cells. It was observed that after the contact inhibition concentration had been reached, the cells grew undisturbed for one more generation. In the following 24 hr the concentration fell back to the level at the beginning of the experiment and stayed there.

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An automatic counter for autoradiographed cells in Petri dishes

Cited by 2 publications

References 1 publication

Insect juvenile hormone activity of optically active alkyl (2E,4E)-3,7,11-trimethyl-2,4-dodecadienoates and of arylterpenoid analogs

Insect juvenile hormone activity of optically active alkyl (2E,4E)-3,7,11-trimethyl-2,4-dodecadienoates and of arylterpenoid analogs

The Kinetics of Contact Inhibition in Mammalian Cells

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