An Autopsy Case of Wegener's Granuloma*

Abstract

progressive gangraenous rhinitis " with a character of sarcoma, then showed severe renal failure, and by autopsy, inflammatory involvement of the nose, glomerulonephritis and generalized arteritis were revealed, -a case corresponding to Wegener's granuloma. majority of autopsy cases are malignant tumors. REPORT OF A CASE Clinical History.-A 17-year-old boy, student, visited the Department of Otorhinolaryngology (Director: Prof. KIRIKAE) of Tokyo University in Feb. 1960, because of nasal occulsion, anonmia, rhinorrhoea and occasional epistaxis that had developed steadily since DCG. 1959-* Directed by Prof. T. YMIDA and Prof. M. MIYAKE 57 SUMMARYAn autopsy case of Wegener's granuloma in a 17-year-old boy that has been clinically diagnosed as so-called gangraenous rhinitis is presented. Granulomatous lesions of the nose, generalized arteritis and typical diffuse glomerulonephritis in the case are described. Short review on literatures and discussion concerning the entity of " gangraenous rhinitis " are made. The authors state that it is necessary to decide the nature of each case that is described clinically as gangraenous rhinitis, whether sarcoma or inflammation.