An easy-to-use heterogeneous catalyst for the Knoevenagel condensation

The condensation of aromatic aldehydes with acidic methylene compounds such as ethyl benzoylacetate, 2,4-pentanedione and dimedone proceeded efficiently in pure water in the presence of L-lysine at room temperature. Interestingly, there are two different reaction mechanisms taking place under the same green catalyst system. This provides a green and mild synthetic method for the preparation of these two classes of compounds.

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Catalysis by L‐Lysine: A Green Method for the Condensation of Aromatic Aldehydes with Acidic Methylene Compounds in Water at Room Temperature

Zhang

Sun

Liang

et al. 2010

Chin. J. Chem.

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ReBr(CO)₅‐Catalyzed Knoevenagel Condensation

Hua

Qiu

2004

Synthetic Communications

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An easy-to-use heterogeneous catalyst for the Knoevenagel condensation

Cited by 2 publications

References 0 publications

Catalysis by L‐Lysine: A Green Method for the Condensation of Aromatic Aldehydes with Acidic Methylene Compounds in Water at Room Temperature

Catalysis by L‐Lysine: A Green Method for the Condensation of Aromatic Aldehydes with Acidic Methylene Compounds in Water at Room Temperature

ReBr(CO)₅‐Catalyzed Knoevenagel Condensation

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An easy-to-use heterogeneous catalyst for the Knoevenagel condensation

Cited by 2 publications

References 0 publications

Catalysis by L‐Lysine: A Green Method for the Condensation of Aromatic Aldehydes with Acidic Methylene Compounds in Water at Room Temperature

Catalysis by L‐Lysine: A Green Method for the Condensation of Aromatic Aldehydes with Acidic Methylene Compounds in Water at Room Temperature

ReBr(CO)5‐Catalyzed Knoevenagel Condensation

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ReBr(CO)₅‐Catalyzed Knoevenagel Condensation