“…Investigators compared interventions involving checklists vs usual care in 7 studies, 28,29,32,36,[38][39][40][41] other practices vs usual care in 3 studies 31,33,35 (although in 1, the usual care scenario included 2 common components of checklists), 35 and other practices vs usual care with checklists already in use in 5 studies. 27,30,34,37,42 The 15 studies excluded because they omitted implementation costs examined maximum sterile barriers 47 ; antibioticimpregnated CVCs 45,46,49,51,52 ; antimicrobial dressings, 15,44,48,53 1-piece vs 2-piece chlorhexidine-gluconate-impregnated dressings, 43 chlorhexidine gluconate vs providone-iodine solutions for insertion site care, 49 standardized maintenance kits vs ad hoc supplies, 54 and disinfection caps for CVC hubs vs scrubbing the hubs. 55,56 Context Thirteen of the 15 unique studies (Table 2) were based in the US, [27][28][29][30][31]33,[35][36][37][38][39][40][41][42] 1 in the United Kingdom, 32 and 1 in Ireland.…”