Petroleum exploration and production in the Niger Delta, Nigeria, has been a significant source of revenue and foreign exchange for the country. Nevertheless, this industry has also been blamed for serious environmental pollution in the region. This review aims to shed light on the implications of petroleum exploration in the Niger Delta region and the resultant environmental damage it has caused. One of the most severe consequences of petroleum exploration in the Niger Delta is the frequent occurrence of oil spills. Due to aging infrastructure, poor maintenance, and criminal activities such as oil theft, pipeline spills have become a recurrent problem. Oil spills lead to the destruction of farmland, loss of biodiversity, poisoning of water sources, and widespread contamination of ecosystems. Petroleum exploration and production activities release substantial pollutants into the atmosphere, posing a significant threat to both human health and the environment. The burning of natural gas during oil production, also known as flaring, is particularly prevalent in the Niger Delta. This practice results in the emission of toxic gases such as carbon dioxide, methane, and sulfur dioxide, contributing to climate change, respiratory diseases, and acid rain. Petroleum exploration in the Niger Delta has led to significant damage to forests and mangrove ecosystems. The destruction of these vital habitats has serious implications for species survival. Oil exploration activities often release harmful chemicals and wastes into the region's water bodies. These pollutants infiltrate the groundwater and surface water, leading to contamination that poses severe risks to human health and aquatic life. Contaminated water supplies have been linked to increased instances of skin diseases, as well as liver and kidney problems among the local population. The negative environmental implications of petroleum exploration in the Niger Delta also have severe socioeconomic consequences. Displaced fishermen and farmers face declining livelihoods, while sporadic employment opportunities generated by the oil industry do not compensate for the long-term damage inflicted on the region.