An economic evaluation of an abdominal aortic aneurysm screening program in Italy

Giardina, S.; Pane, Bianca; Spinella, Giovanni; Cafueri, Giuseppe; Corbo, Mara; Brasseur, P; Orengo, Giovanni; Palombo, Domenico

doi:10.1016/j.jvs.2011.03.264

Cited by 39 publications

(24 citation statements)

References 24 publications

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“…Although previous research has found that preventive services often do not save money, 26,27 AAA screening does provide an opportunity to save lives at a modest cost. [1][2][3][4][5]15,18 Our results require action from policy makers to increase utilization of AAA screening and to ensure its availability to populations for which it represents good value. To ensure the best value from screening, it is important to target those populations most at risk.…”

Section: Resultsmentioning

confidence: 96%

“…1 Other studies have also reported favorable cost-effectiveness for the screening of men for AAA. [2][3][4][5] Despite the availability of the AAA screening benefit and its cost-effectiveness, recent reports indicate very low uptake. 6 One study of Medicare claims data from 2004 to 2008 found that fewer than 10 % of eligible men aged 65 years received any abdominal ultrasonography after 2007.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Abdominal Aortic Aneurysm Screening: How Many Life Years Lost from Underuse of the Medicare Screening Benefit?

et al. 2014

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Section: Resultsmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Abdominal Aortic Aneurysm Screening: How Many Life Years Lost from Underuse of the Medicare Screening Benefit?

et al. 2014

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“…While in many countries screening programs for AAAs have been implemented in the last 15 years [23], [24], in Italy implementation has been limited generally [25], [26]. However, in the Emilia-Romagna region, in the last decades, the use of ultrasonography has become widespread and diagnostic skills have improved, resulting in a greater ability to detect AAAs.…”

Section: Discussionmentioning

confidence: 99%

Hospitalization Rates and Post-Operative Mortality for Abdominal Aortic Aneurysm in Italy over the Period 2000–2011

Sensi¹,

Tedesco

Mimmi

et al. 2013

PLoS ONE

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BackgroundRecent studies have reported declines in incidence, prevalence and mortality for abdominal aortic aneurysms (AAAs) in various countries, but evidence from Mediterranean countries is lacking. The aim of this study is to examine the trend of hospitalization and post-operative mortality rates for AAAs in Italy during the period 2000–2011, taking into account the introduction of endovascular aneurysm repair (EVAR) in 1990s.MethodsThis retrospective cohort study was carried out in Emilia-Romagna, an Italian region with 4.5 million inhabitants. A total of 19,673 patients hospitalized for AAAs between 2000 and 2011, were identified from the hospital discharge records (HDR) database. Hospitalization rates, percentage of OSR and EVAR and 30-day mortality rates were calculated for unruptured (uAAAs) and ruptured AAAs (rAAAs).ResultsAdjusted hospitalization rates decreased on average by 2.9% per year for uAAAs and 3.2% for rAAAs (p<0.001). The temporal trend of 30-day mortality rates remained stable for both groups. The percentage of EVAR for uAAAs increased significantly from 2006 to 2011 (42.7 versus 60.9% respectively, mean change of 3.9% per year, p<0.001). No significant difference in mortality was found between OSR and EVAR for uAAAs and rAAAs.ConclusionsThe incidence and trend of hospitalization rates for rAAAs and uAAAs decreased significantly in the last decade, while 30-day mortality rates in operated patients remained stable. OSR continued to be the most common surgery in rAAAs, although the gap between OSR and EVAR recently declined. The EVAR technique became the preferred surgery for uAAAs since 2008.

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“…Unfortunately, this is not the case in other countries, which cannot afford such high cost of implementing such a wide screening program [80]. More specifically, in a recent study [81], it was shown that the individual cost per invited subject was €60 (US $83.2) and 0.011 additional quality adjusted life years (QALY) were gained per patient in the screened cohort, corresponding to an incremental cost-effectiveness ratio (ICER) of €5673/QALY (US $7870/QALY). These numbers are unlikely to be feasible in a period of world economic crisis.…”

Section: Discussionmentioning

confidence: 99%

Novel Biomarkers of Abdominal Aortic Aneurysm Disease: Identifying Gaps and Dispelling Misperceptions

Moris

Mantonakis

Avgerinos

et al. 2014

BioMed Research International

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Abdominal aortic aneurysm (AAA) is a prevalent and potentially life-threatening disease. Early detection by screening programs and subsequent surveillance has been shown to be effective at reducing the risk of mortality due to aneurysm rupture. The aim of this review is to summarize the developments in the literature concerning the latest biomarkers (from 2008 to date) and their potential screening and therapeutic values. Our search included human studies in English and found numerous novel biomarkers under research, which were categorized in 6 groups. Most of these studies are either experimental or hampered by their low numbers of patients. We concluded that currently no specific laboratory markers allow screeing for the disease and monitoring its progression or the results of treatment. Further studies and studies in larger patient groups are required in order to validate biomarkers as cost-effective tools in the AAA disease.

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An economic evaluation of an abdominal aortic aneurysm screening program in Italy

Abstract: As in economic evaluations developed in other countries, such as the UK, Canada, and The Netherlands, setting up a screening program for AAA can be considered cost-effective from the Italian NHS perspective.

Cited by 39 publications

References 24 publications

Abdominal Aortic Aneurysm Screening: How Many Life Years Lost from Underuse of the Medicare Screening Benefit?

Abdominal Aortic Aneurysm Screening: How Many Life Years Lost from Underuse of the Medicare Screening Benefit?

Hospitalization Rates and Post-Operative Mortality for Abdominal Aortic Aneurysm in Italy over the Period 2000–2011

Novel Biomarkers of Abdominal Aortic Aneurysm Disease: Identifying Gaps and Dispelling Misperceptions

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