“…With the increase of storage capacity and computing power, data-driven fault diagnosis methods have been widely used in chemical processes [4,5]. Among these methods, the multivariate statistical method, mainly including principal component analysis (PCA) [6,7], partial least squares (PLS) [8,9], independent components analysis (ICA) [10,11], Fisher discriminant analysis (FDA) [12,13], random forest (RF) [14], canonical correlation analysis (CCA) [15], exponential discriminant analysis (EDA) [16], and their derivatives [17][18][19][20][21][22], have also made a rapid progress. Although certain effects have been achieved by these data-driven methods, there are still two shortcomings: On one hand, most of these methods rely on an assumption of a single data distribution (e.g., Gaussian distribution) [23,24].…”