An effective method to use ionic liquids as reaction media for asymmetric reduction by Geotrichum candidum

Recent progress in biocatalysis for asymmetric oxidation and reduction

“…For example, Figure 36 shows the asymmetric reduction by a crude alcohol dehydrogenase, dried cells of G. candidum, in hydrophobic ionic liquid ([bmin]PF 6 ). 9 When the cell was immobilized on water-absorbing polymer containing water, the reaction proceeded smoothly with excellent enantioselectivity, while the reaction without the immobilization on polymer did not proceed.…”

Effect of temperature on mixing thermodynamics of a new ionic liquid: {2-Hydroxy ethylammonium formate (2-HEAF)+short hydroxylic solvents}

“…Other main benefits of ionic liquids are their large liquid state range, favourable solvation behaviour, low melting temperature, stability in air, high ionic conductivity, and modification of selectivity in chemical reactions, which open new possibilities in various industrial fields as catalysis, separation techniques, and electrochemical devices building. Recently, the utility of the ionic liquids as solvents for various organic reactions [4][5][6][7][8][9][10][11] has been studied. The most common ionic liquid, 2-butyl imidazolinium salt has proved to be very useful in preparing fast switching electrochromic devices [12], when used as solvent for p-conjugated polymers.…”

Yeast‐Mediated Stereoselective Synthesis

“…However, the process of optimizing the conditions for these reactions might be lengthy but rewarding [385]. The alternative use of Geotrichum candidum has been suggested, and for several substrates excellent enantioselectivity was reported [386].…”