This paper proposed a novel adaptive robust backstepping control scheme for DC-DC buck converter subjected to external disturbance and system uncertainty. Uncertainty in the load resistance and the input voltage represent the big challenge in buck converter control. In this work, an adaptive estimator for matched and mismatched uncertainties based backstepping control is applied for DC-DC buck converter. The updating laws are determined based on the lyapunov theorem. Thus, the difference between the estimated parameters and actual parameters converges to zero. The proposed control method is compared with the conventional sliding mode control and integral sliding mode control. Simulation results demonstrate the effectiveness and robustness of the proposed controller.