An efficient facile and one-pot synthesis of 2-arylsubstituted benzimidazole derivatives using 1-methyl-3-(2-oxyethyl)-1H-imidazol-3-ium-borate sulfonic acid as a recyclable and highly efficient ionic liquid catalyst at green condition

Abstract

1-Methyl-3-(2-oxyethyl)-1H-Imidazol-3-ium-Borate Sulfonic Acid ([MOEI]-BSA) was easily prepared and used as a new and highly efficient solid acid catalyst for the synthesis of benzimidazole derivatives with high isolated yields. Various substituted benzimidazoles were synthesized by a combination of o-phenylenediamines and aldehydes in the presence of [MOEI]-BSA with excellent yields in water and under a mild and green reaction conditions. This method is also applicable for precursors such as aromatic and unsaturated aldehydes and o-phenylenediamines. Addition of organic part to BSA and synthesis of [MOEI]-BSA as a new Bronsted acidic ionic liquid (BAIL) improved the efficiency of this catalyst.

Optimization of the naphtha hydro treating unit (NHT) in order to increase feed in the refinery

“…Due to the abundant hoarding accumulated in the feed surge drum, feed stopping from the unit boundary isn't so problematic. Although it is necessary for the operator to pay attention to the hold-up volume and the time at its disposal and dispels, the problem of stopping the feeder pump is resolved as soon as possible [36]. Loss of feed is more acute due to the problem in the feed pump.…”

UV-visible light-induced photochemical synthesis of benzimidazoles by coomassie brilliant blue coated on W–ZnO@NH2nanoparticles

“…The other important and common factor in all methods disclosed for the preparation of benzimidazoles is due to the existence of a suitable catalyst. So far, various catalysts have been used to synthesize these compounds such as magnetic catalysts, 24 porous materials, 25 metal–organic frameworks, 26 ionic liquids, 27 heavy metal oxides, 28 graphene oxide 29 and so on. By consideration of all the existing literature, we wish to disclose a new heterogeneous photocatalyst in the preparation of 2-substituted benzimidazoles by the reaction of some substituted o -substituted anilines with benzyl alcohols in the presence of air, as the source of oxidizing agent, under the photocatalytic conditions ( Scheme 1 ).…”

Selective photocatalytic oxidation of aromatic alcohols to aldehydes with air by magnetic WO3ZnO/Fe3O4. In situ photochemical synthesis of 2-substituted benzimidazoles

“…32 Considering such a wide range of biological functionalities, extensive efforts have been made to the progress of efficient strategies for the synthesis of various 2-substituted benzimidazoles. Condensation of 2-aminothiophenol, o-phenylenediamine, and 2-aminophenol with aromatic aldehydes under acidic conditions is the well-known method to prepare these drugs 33 by the mediation of various catalysts such as magnetic catalysts, 34 porous catalysts, 35 metal-organic framework catalysts, 36 ionic liquid catalysts, 37 heavy metal catalysts, 38 graphene oxides 39 and so on. Moreover, quinoxalines are also important heteroaromatic compounds that have drawn extensive attention for use in many pharmaceuticals, 40,41 various biofunctional molecules, 42 semiconductor materials 43 and organic synthons.…”