An efficient fluorescence chemosensor for sensing Zn(II) ions and applications in cell imaging and detection of Zn(II) induced aggregation of PrP(106–126) peptide

Modulating the aggregation of human prion protein PrP106–126 by an indole-based cyclometallated palladium complex

“…The aggregates of PrP 106–126 were created following prior publications. 78 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) was used to eliminate any remnants of preformed aggregates of PrP 106–126 . The peptide solution was left overnight, and each aliquot of peptides was then stored at −80 °C after HFIP was evaporated from them using N 2 gas.…”

Tri-armed Schiff base fluorescent sensor for the rapid recognition of Zn(ii): application in live cell imaging, test strips and TLC

“…Despite some Zn( ii ) fluorescent chemosensors demonstrating excellent efficiency, their practical uses are limited by their laborious synthetic procedures and uncertain toxicity. 28–30 Hence, the design and development of novel fluorescent chemosensors for the selective and sensitive detection of intracellular Zn( ii ) remains an essential and highly desirable area for research. 31,32…”