An efficient, one-pot, synthesis of dithiocarbamates from the corresponding alcohols using Mitsunobu’s reagent

Investigation of the Reaction of In Situ Prepared Dithiocarbamic Acids with Itaconic Anhydride in Water

“…Dithiocarbamates, which are analogues of carbamates, have received significant attention because of their unique biological activities , their important role in organic synthesis as efficient intermediates , and many other applications . Besides the traditional methods available for the synthesis of dithiocarbamates, these compounds could be simply prepared via the reaction of an amine, carbon disulfide, and an electrophile including alkyl halides, α,β‐unsaturated carbonyl compounds, epoxides, and aldehydes .…”

Practical approach to 2-thioxo-2,3-dihydroquinazolin-4(1 H )-one via dithiocarbamate–anthranilic acid reaction

“…However the difficult handling of unstable isothiocyanate as well as preparation of costly and toxic reagents, such as thiophosgene limits its practical applications. On the other hand, the dithiocarbamates are safe and highly efficient equivalent to isothiocyanate and were found to show broad application owing to their easy preparation in large scale from simple and readily available starting material [28][29][30][31][32][33][34]. In this context, our interest in green synthesis of dithiocarbamate derivatives [35,36], we aimed to develop an efficient and facile approach to synthesize a series of thioxoquinazolin-4(1H)-ones from dithiocarbamate derivatives under the mild and safe conditions.…”

A Facile and Efficient One-Pot Regioselective Synthesis of 2-Hydroxyalkyl Dithiocarbamates under Catalyst-Free Conditions

“…They also act as linkers in the solid-phase organic synthesis [20][21][22], and for protection of amine groups in peptide synthesis [23]. They are usually synthesized by several available methodologies [24][25][26][27][28][29][30][31][32][33].…”