An Efficient Recyclable Polymer Supported Copper(II) Catalyst for C–N Bond Formation by N-Arylation

Abstract

Polymer supported Cu(II) catalyst was prepared, characterized and employed for the N-arylation and amination reaction of N-H heterocycles with aryl halides as well as arylboronic acids to afford the corresponding coupled products in good to excellent yields. This catalyst can be used several times with consistent catalytic activity.

Synthesis of a reusable polymer anchored cobalt(II) complex for the aerobic oxidation of alkyl aromatics and unsaturated organic compounds

“…The shoulder peaks nearer to 315 nm are attributed to the nep* transition of the azo (eN]Ne) group [31]. The high intensity bands in the visible region, at 400e520 nm involving the whole electronic system of the PS-Co(II)-PAR catalyst are assigned to the pep* transition [32].…”

Nitro resin supported copper nanoparticles: An effective heterogeneous catalyst for C N cross coupling and oxidative C C homocoupling

“…Most of these methods are homogeneous in nature which makes the recovery of catalyst difficult and the presence of stabilizing ligands further complicates the catalytic reaction. Performing these reactions under heterogeneous conditions is favorable as it facilitates work-up, recovery and reusability of the catalyst for multiple reaction cycles [44][45][46].…”

Pd(0)‐guanidine@MCM‐41: a very effective catalyst for rapid production of bis (pyrazolyl)methanes

“…Pyrazoles or pyrazolones [e.g. bis (pyrazolyl)methanes] are a significant category of bioactive drug goals in the pharmaceutical industry that show a variety of biological and medicinal activities, such as anti‐HIV, antiviral, gastric secretion stimulatory, antifilarial, antioxidant, antihypertensive, anticancer, anti‐inflammatory, antimalarial, antidepressant, antimicrobial, antipyretic and antibacterial properties. There are two ways to prepare bis (pyrazolyl)methanes: (i) the one‐pot pseudo five‐component reaction among phenylhydrazine, ethyl acetoacetate and aromatic aldehydes; and (ii) the one‐pot pseudo three‐component reaction between 3‐methyl‐1‐phenyl‐1H‐pyrazol‐5(4H)‐one and aromatic aldehydes.…”