“…For this aim, we used 2-(2,3,4,9tetrahydro-1H-carbazol-2-yl) acetonitrile (1) as a starting material, which was synthesized according to the literature via the Fischer-indol method [39,40], succeeding the synthetic sequence represented in Scheme 1. In this way, the reduction of 1 with BH3.THF to compound 2 (88% yield) was pursued by treatment of TCB, leading to the procreation of the structure 3 [41]. At this point, the efficient construction of the cyclization substrates was essential to reach to our synthetic plan successfully.…”