Microbubble-mediated ultrasound therapies have a common need for methods that can noninvasively monitor the treatment. One approach is to use the bubbles' acoustic emissions as feedback to the operator or a control unit. Current methods interpret the emissions' frequency content to infer the microbubble activities and predict therapeutic outcomes. However, different studies placed their sensors at different angles relative to the emitter's axis and bubble cloud. Here, whether such angles influence the captured emissions is evaluated. The hypothesis is that a bubble cloud's emission is angle-dependent, because the bubbles emit sound at different times as the excitation pulse pass through them. 128 coupled microbubbles and the corresponding readings of two sensors placed at different angles were simulated. The simulation was replicated in experiments using a microbubble-filled gel channel. In both the simulation and the experiments, the first sensor captured a periodic time-domain signal of the bubbles' expansion and collapses, which had high contributions from the first three harmonics. In contrast, the second sensor captured more chaotic time-domain features, which had much higher harmonic and broadband content. Thus, by placing acoustic sensors at different positions, substantially different acoustic emissions were captured, potentially leading to very different conclusions about the treatment outcome.