An electrochemical chlorpromazine sensor based on a gold–copper bimetallic synergetic molecularly imprinted interface on an acupuncture needle electrode

Abstract

Chlorpromazine (CPZ) is a medicine for nervine disease. Measuring CPZ in vivo can assist doctors in evaluating patients’ blood drug concentration and monitoring drug metabolism. Therefore, an accurate in vivo...

A modified electrode based on a 3D reduced graphene oxide and MoS2 composite for simultaneous detection of sunset yellow and tartrazine

“…Based on the Randles–Sevcik equation, 2 the electrically active surface area of 3DrGO–MoS 2 /GCE (0.189 cm 2 ) is larger than that of 3DrGO/GCE (0.145 cm 2 ), MoS 2 /GCE (0.134 cm 2 ) and bare GCE (0.053 cm 2 ), which are approximately equal to the geometric area of these electrodes. 28 This further verifies that the 3DrGO–MoS 2 composite provides a large electrically active surface with good conductivity. EIS is an important technique for studying the interface properties of modified electrodes.…”

A mesothelin microsensor based on an embedded thionine electronic medium within an imprinted polymer on an acupuncture needle electrode

“…Therefore, AuNPs can easily bind with bioactive substances. 20 Moreover, the deposition of these AuNPs can also significantly enhance the electroactive surface area of the AN. Sulfhydryl groups are strongly nucleophilic functional groups.…”

“…These AN microelectrodes (ANMEs) have unique features that are potentially useful for the construction of microsensors or microdetectors compared with traditional planar disc electrodes, microneedles or carbon fiber electrodes. 17–19 Modified acupuncture needles have been electrochemically used to detect 5-HT, 17 chlorpromazine, 20 dopamine, 21 adrenaline 22 and other substances. 23 The detection of protein by AN sensors should be further researched.…”

Electrochemical Sensor Based on Electrodeposited Zinc-Aluminium Layered Double Hydroxide Modified Glassy Carbon Electrode for Chlorpromazine Sensing

“…In response to these challenges, some researchers have ventured into the development of electrochemical chlorpromazine sensors through the electrodeposition of Au/Cu nanoparticles onto acupuncture needles, Ni Al layered double hydroxide (LDH) onto glassy carbon (GC) substrates, and dual-monomer molecularly imprinted polymers onto Pt/Co 3 O 4 electrodes. 18,36,37 These innovative sensor platforms have demonstrated commendable stability and repeatability attributes, which can be attributed to the precise control over the uniformity and thickness of the electrodeposited material on the electrode surface, achieved through fine-tuning electrodeposition parameters.…”