An Electrode Array Sensor for Tongue Cancer Detection With Bioelectrical Impedance Spectroscopic Tomography

Hu, Songpei; Gao, Gui‐Feng; Hong, Zhiyang; Liu, Chang; Liu, Kai; Yao, Jiafeng

doi:10.1109/jsen.2022.3184342

Cited by 5 publications

(1 citation statement)

References 33 publications

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“…Bioimpedance spectroscopy (BIS) concerns the conductive and dielectric properties of organisms when a weak alternating current below the excitation threshold passes through them [1]. Due to its advantages of non-invasiveness, low cost and simple operation, BIS has been widely used in clinical research, for example in body composition analysis [2], cancer detection and evaluation [3,4], biological cell detection [5], biological tissue detection and evaluation [5,6], and human organ status monitoring and analysis [7].…”

Section: Introductionmentioning

confidence: 99%

Bioimpedance spectroscopy measurement method based on multisine excitation and integer-period undersampling

Hong

Zhang

et al. 2023

Meas. Sci. Technol.

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Bioimpedance spectroscopy (BIS) is a detection technology that uses the bioimpedance characteristics and changes law of human tissue to analyze its physiological and pathological states, and is widely used in clinical and scientific research applications. Traditional BIS measurement needs to satisfy the Nyquist sampling theorem, so as to ensure that the measurement signal has no frequency aliasing, but at the same time, the sampling frequency and the number of sampling points will be increased, which will increase the computation and hardware cost. This paper proposes a novel BIS measurement method based on multisine excitation and integer-period undersampling (IPUS) technology. Firstly, the multisine-based IPUS theory was deduced, and the BIS measurement principle based on multisine excitation and IPUS technology was introduced. Secondly, a BIS measurement system based on FPGA+ADC+DAC architecture was designed, and a multisine excitation with 32 pseudo-logarithmically distributed frequency components in the range of 2-997 kHz was generated. The comparative BIS measurement experiments on three RC three-element models were carried out under the Nyquist sampling condition (fs = 2.56 MHz) and under the IPUS condition (fs = 512 kHz), respectively. Experimental results showed that the average amplitude error of BIS measurement under the Nyquist sampling condition is 0.80% (mean) ± 1.19% (std), while the average amplitude error under the IPUS condition is 1.02% (mean) ± 1.13% (std). Moreover, the signal to nosie ratio (SNRz) is calculated in 40 repeated BIS measurements, where the mean SNRz is 63.60dB under IPUS condition, similar to the value of 62.77dB under Nyquist sampling condition. The proposed multisine-based IPUS theory and its implementation method in this paper can complete a BIS measurement with only one fundamental period, and need the sampling frequency and sampling points lower than the requirements of the Nyquist theory, which lay a theoretical and technical foundation for BIS measurement system with reduced hardware requirements and computation cost.

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Section: Introductionmentioning

confidence: 99%

Bioimpedance spectroscopy measurement method based on multisine excitation and integer-period undersampling

Hong

Zhang

et al. 2023

Meas. Sci. Technol.

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Toward Continuous Nano-Plastic Monitoring in Water by High Frequency Impedance Measurement With Nano-Electrode Arrays

2023

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We explore the potentiality of high frequency impedance measurements with CMOS nano-electrode arrays for nano-plastic pollutant particles monitoring in water. This technology offers benefits as nano-scale resolution, high parallelization, scalability, label-free single particle detection, and automatic measurements without operator intervention. Simple models are proposed for size and concentration estimation. The former integrates measurements of adjacent electrodes and shows uncertainty comparable to the nominal one with mean prediction error lower than 45 % down to 50 nm radius. The latter accounts for noise in the definition of the sensing volume. We report a worst-case concentration error lower than a factor 1.7 under stationary and continuous flow, which demonstrates the potential of this technology for automated measurements.

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Position and Intensity Sensing of a Large-Area Tactile Sensor for Hands-on Detection in Conditional Autonomous Driving

Chen,

Jin,

Qin

et al. 2024

IEEE Sensors J.

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An Electrode Array Sensor for Tongue Cancer Detection With Bioelectrical Impedance Spectroscopic Tomography

Cited by 5 publications

References 33 publications

Bioimpedance spectroscopy measurement method based on multisine excitation and integer-period undersampling

Bioimpedance spectroscopy measurement method based on multisine excitation and integer-period undersampling

Toward Continuous Nano-Plastic Monitoring in Water by High Frequency Impedance Measurement With Nano-Electrode Arrays

Position and Intensity Sensing of a Large-Area Tactile Sensor for Hands-on Detection in Conditional Autonomous Driving

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