An elegant and efficient synthesis of heterocycles integrated with bis‐N‐acyl pyrazoline and bis‐1, 2, 3‐triazole via a green synthetic methodology

Abstract

Highly efficient and sustainable one-pot multicomponent synthetic protocol has been accomplished for the synthesis of novel bis-N-substituted pyrazolinyl-1, 2, 3-triazole hybrids from readily available starting materials via operationally simple mechanochemical grinding approach. The present solvent-free synthetic protocol is advantageous for being atom economic involving short reaction time, ambient temperature, and non-chromatographic separation of products.