An endoscopic imaging system for co-registered Doppler optical coherence tomography and autofluorescence imaging of human airways in vivo

Pahlevaninezhad, Hamid; Lee, Anthony M. D.; Marsh, R.C.; Lam, Stephen; MacAulay, Calum E.; Lane, Pierre

doi:10.1364/boda.2015.bm4a.4

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2017

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“…12,15,[23][24][25][26][27][28] To achieve 3-D imaging, a pullback mechanism along the probe can be added either manually or mechanically. [29][30][31][32] In colposcopic imaging, however, the OCT probe does not require flexibility and only needs a relative short probe length (around 10 cm). In addition, a colposcopic OCT probe can be designed with a much larger diameter (several millimeters) as compared with vascular endoscopic OCT probes.…”

Section: Introductionmentioning

confidence: 99%

Colposcopic imaging using visible-light optical coherence tomography

et al. 2017

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Abstract. High-resolution colposcopic optical coherence tomography (OCT) provides key anatomical measures, such as thickness and minor traumatic injury of vaginal epithelium, of the female reproductive tract noninvasively. This information can be helpful in both fundamental investigations in animal models and disease screenings in humans. We present a fiber-based visible-light OCT and two probe designs for colposcopic application. One probe conducts circular scanning using a DC motor, and the other probe is capable of three-dimensional imaging over a 4.6 × 4.6-mm 2 area using a pair of galvo scanners. Using this colposcopic vis-OCT with both probes, we acquired high-resolution images from whole isolated macaque vaginal samples and identified biopsy lesions.

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