Three algorithms (the Charge Comparison Method, n-γ Model Analysis and the Centroid Algorithm) have been revised to improve their accuracy and broaden the scope of applications to real-time digital n-γ discrimination. To evaluate the feasibility of the revised algorithms, a comparison between the improved and original versions of each is presented. To select an optimal real-time discrimination algorithm from these six algorithms (improved and original), the figure-of-merit (FOM), Peak-Threshold Ratio (PTR), Error Probability (EP) and Simulation Time (ST) for each were calculated to obtain a quantitatively comprehensive assessment of their performance. The results demonstrate that the improved algorithms have a higher accuracy, with an average improvement of 10% in FOM, 95% in PTR and 25% in EP, but all the STs are increased. Finally, the Adjustable Centroid Algorithm (ACA) is selected as the optimal algorithm for real-time digital n-γ discrimination.