An enormous hepatitis B virus‐related liver disease burden projected in Vietnam by 2025

Nguyen, Van Thi Thuy; Law, Matthew; Dore, Gregory J.

doi:10.1111/j.1478-3231.2007.01646.x

Cited by 64 publications

(68 citation statements)

References 40 publications

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“…However, the HBV-related liver disease burden from cirrhosis and HCC will continue to rise on the basis of the estimated incidence with HBV DNA levels from the Taiwanese Risk Evaluation of Viral Load Elevation and Associated Liver Disease/Cancer in HBV (REVEAL-HBV) study [47,48]. Estimated HBV-related mortality is expected to increase from 12,600 in 1990 to 40,000 in 2025 [49]. A national HBV strategy is required to address this expanding burden of liver disease.…”

Section: Prevention Of Mother-to-child Transmissionmentioning

confidence: 99%

Chronic hepatitis B in Asian women of childbearing age

Leung

2009

Hepatol Int

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Hepatitis B virus (HBV) infection is a serious clinical problem affecting approximately 2 billion people worldwide. An estimated 350 million live with chronic hepatitis B (CHB) infection and are at an increased risk for serious liver sequelae and death from acute or chronic consequences of CHB infection. Individuals with CHB have a 20-30% risk of early death from complications, including liver cirrhosis and hepatocellular carcinoma. In the Asia-Pacific region, half of the CHB burden results from vertical or mother-to-child transmission, with early childhood horizontal transmission accounting for the remaining half. Screening and vaccination are key factors in the successful prevention and control of HBV infection. Over the last 20 years, the implementation of screening programs and universal HBV vaccination for all individuals born in endemic areas have reduced the prevalence of HBV infection and HBV-related liver diseases among individuals younger than 30 years. Women of childbearing age are key stakeholders in preventing HBV infection and, as such, play a critical role in reducing the vertical and horizontal transmission of HBV. Further efforts are needed to implement screening and educational programs for women of childbearing age, particularly those with CHB, to prevent the transmission of HBV to newborns, spouses, other household members, and sexual partners. In addition, healthcare workers need to learn how to avoid iatrogenic transmission in the healthcare setting. This article reviews these issues and highlights areas in which their engagement with public health efforts serves to improve quality of life and society as a whole.

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Section: Prevention Of Mother-to-child Transmissionmentioning

confidence: 99%

Chronic hepatitis B in Asian women of childbearing age

Leung

2009

Hepatol Int

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“…17 Mathematical models estimate nationally that by 2013, the number of people with chronic HBV infection will reach its peak at 8.6 million cases and then decrease to 8 million by 2025, as a direct impact of the universal infant vaccination. 42 However, the prevention of new infections does not affect the progression of the already infected individuals, and thus the estimates suggest liver cancer and liver cirrhosis cases will continue to increase: liver cirrhosis will increase from 36 500 cases in 2005 to 58 600 in 2025 and liver cancer will increase from 15 600 in 2005 to 25 000 in 2025. 42 As a result, the estimated annual HBV-related deaths will increase from 23 300 in 2005 to 40 000 in 2025.…”

Section: Burden Of Viral Hepatitis and Liver Diseasesmentioning

confidence: 99%

“…42 However, the prevention of new infections does not affect the progression of the already infected individuals, and thus the estimates suggest liver cancer and liver cirrhosis cases will continue to increase: liver cirrhosis will increase from 36 500 cases in 2005 to 58 600 in 2025 and liver cancer will increase from 15 600 in 2005 to 25 000 in 2025. 42 As a result, the estimated annual HBV-related deaths will increase from 23 300 in 2005 to 40 000 in 2025. 42 Ngo et al have found that liver cancer and liver diseases were the fourth and sixth causes of deaths among males, respectively, and that liver cancer was the third cause of death among females, between 15 and 59 years of age.…”

Section: Burden Of Viral Hepatitis and Liver Diseasesmentioning

confidence: 99%

“…42 As a result, the estimated annual HBV-related deaths will increase from 23 300 in 2005 to 40 000 in 2025. 42 Ngo et al have found that liver cancer and liver diseases were the fourth and sixth causes of deaths among males, respectively, and that liver cancer was the third cause of death among females, between 15 and 59 years of age. 43 Nevertheless, among cancer-related deaths, liver cancer was ranked as the leading cause, with 31.0% among males and 19.9% among females, followed by lung and stomach cancers.…”

Section: Burden Of Viral Hepatitis and Liver Diseasesmentioning

confidence: 99%

“…45 With an estimation of more than 8 million individuals infected with HBV or HCV in Vietnam, viral hepatitis represents an important burden on the health and economic sectors. 42 In addition, since progression to liver diseases and liver cancer takes many years, an even greater burden is to be expected in coming decades.…”

Section: Burden Of Viral Hepatitis and Liver Diseasesmentioning

confidence: 99%

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Epidemiology, Responses, and Way Forward

Sereno

Mesquita²,

Kato³

et al. 2012

Journal of the International Association of Physicians in AIDS

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Viral hepatitis is a disease of great concern to public health that is now met by a favorable momentum to combat the global epidemic. This article is intended to highlight the importance of viral hepatitis in the Vietnam population as well in the group of people living with HIV/AIDS (PLWHA). We reviewed available data on epidemiology and response on hepatitis B virus (HBV) and hepatitis C virus (HCV) and HIV coinfection in Vietnam. The hepatitis B surface antigen (HBsAg) prevalence in the general population ranged from 5.7% to 24.7%. The anti-HCV prevalence ranged from 0.38% to 4.3% in the general population, while among people who inject drugs (PWIDs) it ranged from 31% to 97.2%. The HBV prevalence among PLWHA is similar to the general population, while HCV/HIV coinfection is concentrated in some groups. Anti-HCV prevalence among HIV-infected PWIDs can be as high as 98.5%. Developing policies for diagnosis and treatment of chronic HBV and HCV infections are critical priorities in order to prevent clinical progression to cirrhosis and liver cancer.

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Cancer incidence among Asian American populations in the United States, 2009-2011

Jin

Pinheiro

et al. 2016

Int. J. Cancer

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Cancer incidence disparities exist among specific Asian American populations. However, the existing reports exclude data from large metropoles like Chicago, Houston and New York. Moreover, incidence rates by subgroup have been underestimated due to the exclusion of Asians with unknown subgroup. Cancer incidence data for 2009 to 2011 for eight states accounting for 68% of the Asian American population were analyzed. Race for cases with unknown subgroup was imputed using stratified proportion models by sex, age, cancer site and geographic regions. Age-standardized incidence rates were calculated for 17 cancer sites for the six largest Asian subgroups. Our analysis comprised 90,709 Asian and 1,327,727 non-Hispanic white cancer cases. Asian Americans had significantly lower overall cancer incidence rates than non-Hispanic whites (336.5 per 100,000 and 541.9 for men, 299.6 and 449.3 for women, respectively). Among specific Asian subgroups, Filipino men (377.4) and Japanese women (342.7) had the highest overall incidence rates while South Asian men (297.7) and Korean women (275.9) had the lowest. In comparison to non-Hispanic whites and other Asian subgroups, significantly higher risks were observed for colorectal cancer among Japanese, stomach cancer among Koreans, nasopharyngeal cancer among Chinese, thyroid cancer among Filipinos, and liver cancer among Vietnamese. South Asians had remarkably low lung cancer risk. Overall, Asian Americans have a lower cancer risk than non-Hispanic whites, except for nasopharyngeal, liver and stomach cancers. The unique portrayal of cancer incidence patterns among specific Asian subgroups in this study provides a new baseline for future cancer surveillance research and health policy.

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An enormous hepatitis B virus‐related liver disease burden projected in Vietnam by 2025

Abstract: Over the next two decades, universal infant HBV vaccination will reduce chronic HBV prevalence in Vietnam but HBV-related liver disease burden will continue to rise. A national HBV strategy is required to address this expanding burden of liver disease.

Cited by 64 publications

References 40 publications

Chronic hepatitis B in Asian women of childbearing age

Chronic hepatitis B in Asian women of childbearing age

Epidemiology, Responses, and Way Forward

Cancer incidence among Asian American populations in the United States, 2009-2011

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