An Epidemic of Ross River Virus Infection in Fiji, 1979

Aaskov, John; Mataika, J. U.; Lawrence, Gary W.; Rabukawaqa, Vilikesa B.; Tucker, M.; Miles, J. A. R.; Dalglish, Debra A.

doi:10.4269/ajtmh.1981.30.1053

Cited by 126 publications

(83 citation statements)

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“…Chikungunya and O'nyong-nyong viruses have caused massive epidemics of acute, debilitating arthralgia in Africa and Asia (reviewed in reference 10). Ross River virus, the etiologic agent of epidemic polyarthritis, is endemic to Australia (2,10,28), and it caused a major epidemic that swept the South Pacific islands in 1979, affecting 50,000 people on the island of Fiji (1). Sindbis-group alphaviruses, including Ockelbo virus, Karelian fever virus, and GirdwoodS.A.…”

mentioning

confidence: 99%

Sindbis-Group Alphavirus Replication in Periosteum and Endosteum of Long Bones in Adult Mice

Heise

Simpson

Johnston

2000

J Virol

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Several alphaviruses, including the Sindbis-group viruses, Ross River virus, O'nyong-nyong virus, and Chikungunya virus, are associated with outbreaks of acute and persistent arthralgia and arthritis in humans. Mechanisms underlying alphavirus-induced arthralgia and arthritis are not clearly understood, though direct viral replication within or around the affected joints is thought to contribute to disease. S.A.AR86 is a Sindbis-group alphavirus closely related to the arthralgia-associated Ockelbo and GirdwoodS.A viruses. Following inoculation with S.A.AR86 derived from a molecular clone, infectious virus was isolated from bone and joint tissue 1 to 6 days postinfection. Studies using either in situ hybridization or S.A.AR86-derived double promoter viruses and replicons expressing green fluorescent protein localized sites of viral replication to the periosteum, tendons, and endosteum within the epiphyses of the long bones adjacent to articular joints. These results demonstrate that alphaviruses associated with arthralgia in humans replicate within bone-associated connective tissue adjacent to articular joints in an adult mouse model.

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mentioning

confidence: 99%

Sindbis-Group Alphavirus Replication in Periosteum and Endosteum of Long Bones in Adult Mice

Heise

Simpson

Johnston

2000

J Virol

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“…In 1979-1980, a Ross River virus outbreak in the Pacific Islands resulted in > 500,000 cases and affected 90% of the population in Fiji, 69% in the Cook Islands, 44% in American Samoa, and 33% in New Caledonia (10)(11)(12). The newly introduced virus was thought to have arrived via a viraemic Australian traveller to Fiji, and is likely to still be circulating at low levels (13).…”

Section: Disease Emergence and Outbreaksmentioning

confidence: 99%

Combating infectious diseases in the Pacific Islands: sentinel surveillance, environmental health, and geospatial tools

Lau

2014

Reviews on Environmental Health

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“…10 There were an estimated 50,000 clinical cases of RRV in Fiji, and more than 300,000 human infections affecting nearly half of the population, and the epidemic eventually spread to other South Pacific nations such as Samoa, Cook Islands, New Caledonia, and Wallis and Futuna Islands. 39 The explosive nature of the outbreak in Fiji was a likely result of low levels of antibodies to RRV in the community, 38 which would also occur in the event of CHIKV outbreak. In New Zealand, this would likely occur in the case of any arbovirus outbreak.…”

Section: South Pacificmentioning

confidence: 99%

“…The scenario for an outbreak of CHIKV could resemble the RRV epidemic that occurred in the South Pacific in 1979, 38,39 which appears to have started with the arrival of an infected human in Fiji, 39 as happened in the CHIKV outbreak in Italy. 10 There were an estimated 50,000 clinical cases of RRV in Fiji, and more than 300,000 human infections affecting nearly half of the population, and the epidemic eventually spread to other South Pacific nations such as Samoa, Cook Islands, New Caledonia, and Wallis and Futuna Islands.…”

Section: South Pacificmentioning

confidence: 99%

Chikungunya Virus: A Novel and Potentially Serious Threat to New Zealand and the South Pacific Islands

Derraik¹,

Slaney²,

Nye³

et al. 2010

The American Society of Tropical Medicine and Hygiene

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There has never been a locally transmitted outbreak of mosquito-borne disease in New Zealand, but the risk of an outbreak occurring is increasing with on-going interceptions of exotic mosquito vectors across its border, increasing traffic of goods and passengers, higher numbers of viremic travelers arriving, and local, regional, and global environmental change. The risk posed to New Zealand by chikungunya virus is potentially high because of the transmissibility of this virus in subtropical climates, compounded by a population that is predominantly immunologically naive to exotic arboviruses. However, risk reduction in New Zealand should not be considered in isolation but must be viewed within a wider South Pacific context. In this report, we discuss the potential threat posed by chikungunya to the region, focusing in particular on New Zealand, and re-emphasizing the need for a South Pacific–wide approach towards mosquito-borne disease prevention.

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An Epidemic of Ross River Virus Infection in Fiji, 1979

Cited by 126 publications

References 0 publications

Sindbis-Group Alphavirus Replication in Periosteum and Endosteum of Long Bones in Adult Mice

Sindbis-Group Alphavirus Replication in Periosteum and Endosteum of Long Bones in Adult Mice

Combating infectious diseases in the Pacific Islands: sentinel surveillance, environmental health, and geospatial tools

Chikungunya Virus: A Novel and Potentially Serious Threat to New Zealand and the South Pacific Islands

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