An Equation for the Prediction of Oxygen Consumption in a Brazilian Population

Abstract

BackgroundThe equations predicting maximal oxygen uptake (VO2max or peak) presently in use in cardiopulmonary exercise testing (CPET) softwares in Brazil have not been adequately validated. These equations are very important for the diagnostic capacity of this method.ObjectiveBuild and validate a Brazilian Equation (BE) for prediction of VO2peak in comparison to the equation cited by Jones (JE) and the Wasserman algorithm (WA).MethodsTreadmill evaluation was performed on 3119 individuals with CPET (breath by breath). The construction group (CG) of the equation consisted of 2495 healthy participants. The other 624 individuals were allocated to the external validation group (EVG). At the BE (derived from a multivariate regression model), age, gender, body mass index (BMI) and physical activity level were considered. The same equation was also tested in the EVG. Dispersion graphs and Bland-Altman analyses were built.ResultsIn the CG, the mean age was 42.6 years, 51.5% were male, the average BMI was 27.2, and the physical activity distribution level was: 51.3% sedentary, 44.4% active and 4.3% athletes. An optimal correlation between the BE and the CPET measured VO2peak was observed (0.807). On the other hand, difference came up between the average VO2peak expected by the JE and WA and the CPET measured VO2peak, as well as the one gotten from the BE (p = 0.001).ConclusionBE presents VO2peak values close to those directly measured by CPET, while Jones and Wasserman differ significantly from the real VO2peak.

Reference values for cardiopulmonary exercise testing in healthy subjects – an updated systematic review

“…Ten studies [29,[33][34][35][36][37][38][39][40][41] reported data for minute ventilation at peak exercise (VE peak ). Almost all studies reported VE peak data using tabulated data.…”

A new equation to predict peak VO2 in obese patients during cardiopulmonary exercise testing

“…The equation that had the greatest overestimate of the obese subjects CRF in this study was developed by Almeida et al . (Almeida et al ., ), with a mean difference of 36 ml min −1 kg −1 (Fig. d).…”

“…For cross-validation, the arithmetic mean between estimated and obtained VO 2 was calculated, and agreement analysis was performed using the Bland and Altman graphic method. We used the same method for comparing estimated and obtained peak VO 2 in three other equations previously developed (Hansen et al, 1984;Vivacqua & Hespanha, 1992;Almeida et al, 2014). Almeida et al recruited Brazilian subjects with a mean age of 42 years of both sexes.…”

Análise comparativa de fórmulas preditivas de avaliação da capacidade funcional com o teste cardiopulmonar de jogadoras de futebol profissional

“…According to another research 22 , when comparing predictive models with formulas already described in the literature, such as ACSM 7 or the formulas advocated by other authors 3 , it was shown that VO 2 could be accurately predicted using body mass index, age and workload as independent variables, when the volunteers are seemingly healthy and not athletes. In another study 23 , the authors developed an equation for the Brazilian population that takes into account the following variables: gender, age, BMI and physical activity level, comparing it with formulas used in the prediction of VO 2 , as that of previous studies 6,7,24 . The results indicated that both formulas overestimated the VO 2 when compared to the equation presented by them.…”