An ethnobotanical survey of mosquito repellent plants in uMkhanyakude district, KwaZulu-Natal province, South Africa

Mavundza, Edison; Maharaj, Rajendra; Finnie, J.F.; Kabera, Gaëtan; Staden, J. Van

doi:10.1016/j.jep.2011.08.040

Cited by 53 publications

(38 citation statements)

References 23 publications

(26 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The repellency in the tunnel tests supported the traditional use of the plant whereby the branches of C. anisata are hung by the windows and doors to keep mosquitoes away (Mavundza et al 2011). With repellency activity not differing significantly over the 3 hours of evaluation, we conclude that the responsible compound(s) are stable and did not vaporise substantially for the extracts to lose their activity over the 3 hour test period.…”

Section: Space Spraying Assaysupporting

confidence: 58%

See 1 more Smart Citation

Repellent and mosquitocidal effects of leaf extracts of Clausena anisata against the Aedes aegypti mosquito (Diptera: Culicidae)

Mukandiwa

Eloff

Naidoo

2016

Environ Sci Pollut Res

View full text Add to dashboard Cite

Mosquitoes are rapidly developing resistance to insecticides that millions of people relied on to protect themselves from the diseases they carry, thereby creating a need to develop new insecticides. Clausena anisata is used traditionally as an insect repellent by various communities in Africa and Asia. For this study, the repellency and adulticidal activities of leaf extracts and compounds isolated from this plant species were evaluated against the yellow fever mosquito, Aedes aegypti. In the topical application assays, using total bites as an indicator, repellency was dose-dependent, with the acetone crude extract (15% ) having 93% repellence and the hexane fraction (7.5%) 67% repellence after 3 h. Fractionation resulted in a loss of total repellence. As mosquito-net treating agents, the acetone and hexane extracts of C. anisata, both at 15%, had average repellences of 46.89 ± 2.95 and 50.13 ± 2.02 %, respectively, 3 h after exposure. The C. anisata acetone extract and its hexane fraction caused mosquito knockdown and eventually death when nebulised into the testing chamber, with an EC 50 of 78.9mg/ml (7.89%) and 71.6 mg/ml (7.16%) in the first 15 minutes after spraying.Clausena anisata leaf extracts have potential to be included in protection products against mosquitoes due to the repellent and cidal compounds contained therein.

show abstract

Section: Space Spraying Assaysupporting

confidence: 58%

“…Benth is widely used against various pests and parasites in many parts of Africa. It is used as a mosquito repellent in some parts of South Africa (Mavundza et al 2011). In Zimbabwe the leaves are used to expel maggots from wounds of animals (Chavunduka 1976).…”

Section: Introductionmentioning

confidence: 99%

Repellent and mosquitocidal effects of leaf extracts of Clausena anisata against the Aedes aegypti mosquito (Diptera: Culicidae)

Mukandiwa

Eloff

Naidoo

2016

Environ Sci Pollut Res

View full text Add to dashboard Cite

show abstract

“…The exposure of a target organism to a group of phytochemicals, rather than to a single active principle, lowers the probability for that organism to develop resistance or behavioural desensitization. Clausena anisata is one of the ethnomedicinal plants that have been reportedly used traditionally to repel or kill mosquitoes (Okunade and Olaifa 1987;Mavundza et al, 2011). It has also been reported to have insecticidal and repellent activities against various insects in ethnoveterinary medicine (Chavunduka, 1976) and in-vitro laboratory studies (Boeke et al, 2004;Ndomo et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Larvicidal activity of leaf extracts and seselin from Clausena anisata (Rutaceae) against Aedes aegypti

Mukandiwa

Eloff

Naidoo

2015

South African Journal of Botany

View full text Add to dashboard Cite

Highlights• Hexane leaf extracts of Clausena anisata cause A. eagypti mosquito larval mortality.• The larvicidal activity is partially attributed to the pyranocoumarin, seselin.• The hexane leaf extract retains larvicidal activity after 2 months of storage. AbstractThe Aedes aegypti mosquito is a vector of various diseases in both humans and livestock.Mosquito control focuses on reducing the longevity as well as the population of mosquitoes to lessen their damage on human and animal health. It entails several strategies such as environmental management, insecticide treatments, and molecular entomological approaches.Environmental management centres on elimination of breeding sites, however mosquitoes can breed in sites that cannot be eliminated. Resultantly, focus is turned onto mosquito larvae control. The objective of this study was to evaluate the larvicidal activity of extracts and compounds from Clausena anisata against A. aegypti. The World Health Organization guidelines for testing of mosquito larvicides were used. The acetone, dichloromethane and hexane crude leaf extracts were evaluated in a preliminary screening for larvicidal activity at 2 the concentrations of 12.5, 25, 50, 100 and 200 ppm. Batches of 25 third-instar larvae were transferred into cups each containing test solutions and larval mortality was recorded 24 h and 48 h after exposure. Acetone was used as the solvent control while permethrin was used as a positive control. Only the n-hexane extract caused mortality at the tested concentrations, thus it was further tested at 40, 60, 80, 100, and 120 ppm and had LC 50 values of 68.30 and 59.65 ppm after 24h and 48h respectively. A stored hexane extract, of 2 months, was also evaluated under simulated field conditions to establish stability of extract. It caused about 90% mortality when tested at 100 ppm. The n-hexane extract was subjected to open column chromatography on silica gel to isolate the active compound. The isolated compound was identified as the pyranocoumarin, seselin. Dose dependent mortality was observed in the larvae exposed to seselin. The LC 50 values at 24 and 48 h were 13.90 and 9.96 ppm respectively. Results obtained from this study indicate a potential of the incorporation of C.anisata extracts into the control of mosquito populations.

show abstract

“…Sustainable conservation approaches should be applied to medicinal plants, and is of utmost importance to protect these plant species and to avoid extinction (Mavundza et al, 2011;Fay, 1992). The use of different plant species to treat the same condition is in itself a conservation endeavour, and ensures that the treatment of one condition is not borne by a single plant species (Semenya et al, 2013).…”

Section: Conservationmentioning

confidence: 99%

“…Sustainable conservation approach should be taken into consideration, to prevent conservation threat and ultimately extinction to local plant populations (Mavundza et al, 2011). To address this, sustainable harvesting of the affected plants as well as enlightening programmes to educate the people in affected areas on medicinal plant conservation is advocated.…”

Section: Conservationmentioning

confidence: 99%

An ethnobotanical survey of medicinal plants used by traditional health practitioners to manage HIV and its related opportunistic infections in Mpoza, Eastern Cape Province, South Africa

Hughes

Tarryn

Oluwaseyi

et al. 2015

Journal of Ethnopharmacology

View full text Add to dashboard Cite

An ethnobotanical survey of mosquito repellent plants in uMkhanyakude district, KwaZulu-Natal province, South Africa

Cited by 53 publications

References 23 publications

Repellent and mosquitocidal effects of leaf extracts of Clausena anisata against the Aedes aegypti mosquito (Diptera: Culicidae)

Repellent and mosquitocidal effects of leaf extracts of Clausena anisata against the Aedes aegypti mosquito (Diptera: Culicidae)

Larvicidal activity of leaf extracts and seselin from Clausena anisata (Rutaceae) against Aedes aegypti

An ethnobotanical survey of medicinal plants used by traditional health practitioners to manage HIV and its related opportunistic infections in Mpoza, Eastern Cape Province, South Africa

Contact Info

Product

Resources

About