“…Red algae are sufficiently distant from terrestrial plants to anticipate substantial metabolic drift compared with the known pathways in organisms such as Arabidopsis thaliana, yet C. crispus has been subject to biological studies for more than two centuries (Collé n et al, 2014). Notably, its genome was sequenced and annotation was performed with a focus on metabolic features (Collé n et al, 2013), and there is extensive literature available describing its metabolome (Young and Smith, 1958;Saito and Idler, 1966;Laycock and Craigie, 1977;Matsuhiro and Urzua, 1992;Karsten et al, 1998;Tasende, 2000;Krä bs et al, 2004;Gaquerel et al, 2007;Banskota et al, 2014;Pina et al, 2014;Melo et al, 2015, Alcaide et al, 1968Goldberg et al, 1982;Kremer and Kirst, 1982;Pettit et al, 1989;van Ginneken et al, 2011;Santos et al, 2015;Robertson et al, 2015;Athukorala et al, 2016;Belghit et al, 2017;Guihé neuf et al, 2018;Lalegerie et al, 2019).…”