An evaluation of lateralizing signs in patients with temporal lobe epilepsy

Ataoglu, Esra Erkoc; Yıldırım, İrem; Bilir, Erhan

doi:10.1016/j.yebeh.2015.04.015

Cited by 13 publications

(8 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Release of mesencephalic and spinal central pattern generators can also contribute to expression of behaviorally distinctive motor sequences . Literature on behavioral sequences that are suggestive of specific lateralization and localization is extensive, whereas literature on individual localizing signs is scarce …”

mentioning

confidence: 99%

Hand posture as localizing sign in adult focal epileptic seizures

Ferando

Soss

Elder

et al. 2019

Annals of Neurology

View full text Add to dashboard Cite

Objective: The aim of this study was to identify specific ictal hand postures (HPs) as localizing signs of the epileptogenic zone (EZ) in patients with frontal or temporal lobe epilepsy. Methods: In this study, we retrospectively analyzed ictal semiology of 489 temporal lobe or frontal lobe seizures recorded over a 6-year period at the Seizure Disorder Center at University of California, Los Angeles in the USA (45 patients) or at the C. Munari Epilepsy Surgery Center at Niguarda Hospital in Milan, Italy (34 patients). Our criterion for EZ localization was at least 2 years of seizure freedom after surgery. We analyzed presence and latency of ictal HP. We then examined whether specific initial HPs are predictive for EZ localization. Results: We found that ictal HPs were present in 72.5% of patients with frontal and 54.5% of patients with temporal lobe seizures. We divided HPs into 6 classes depending on the reciprocal position of the fingers ("fist," "cup," "politician's fist," "pincer," "extended hand," "pointing"). We found a striking correlation between EZ localization and ictal HP. In particular, fist and pointing HPs are strongly predictive of frontal lobe EZ; cup, politician's fist, and pincer are strongly predictive of temporal lobe EZ. Interpretation: Our study offers simple ictal signs that appear to clarify differential diagnosis of temporal versus frontal lobe EZ localization. These results are meant to be used as a novel complementary tool during presurgical evaluation for epilepsy. At the same time, they give us important insight into the neurophysiology of hand movements.

show abstract

mentioning

confidence: 99%

Hand posture as localizing sign in adult focal epileptic seizures

Ferando

Soss

Elder

et al. 2019

Annals of Neurology

View full text Add to dashboard Cite

show abstract

“…Ancak klinik ve nörogörüntüleme yöntemleri ile korele edildiğinde odağın saptanması daha kolay hale gelmektedir ve ameliyat sonrası nöbetsizlik oranı artmaktadır. [2][3][4][5][6] Auralar TLE'de aura tipinin iyi tanımlanabilirse oldukça güçlü şekilde lateralize edici olabileceği bilinmektedir. [17] Aura sıklığı çalışmalarda değişkenlik göstermekte olup, %22-83 oranlarında bildirilmiştir.…”

Section: Discussionunclassified

“…[4] Bu otonomik belirtinin TLE'sinde sıklığı %0.3-8 arasında değişmektedir. [5,37] Literatürde bildirilen peri-iktal üriner dürtü hissi nondominant hemisfer ile ilişkili bulunmuştur. [5,37,38] Bizim serimizde iktal -postiktal işeme/işeme ihtiyacı 12 nöbette (%3.4) izlendi.…”

Section: Discussionunclassified

“…Güvenilir lateralize klinik belirtilerin varlığı ameliyattan sonra nöbetsiz olacak hastaların tespit edilmesinde önemlidir. [1][2][3][4][5][6][7] Klasik ve lateralizan değeri yüksek semiyolojik belirtilerin yanında daha az sıklıkta karşılaşılan ve literatürde laterizasyon açısından tartışmalı belirtiler de gözlenmektedir. [3][4][5][6][7] Özellikle peri-iktal vejetatif semptomlar ile klinik çalışmalar sınırlı sayıdadır ve çoğu olgu düzeyinde bildirimlerdir.…”

Section: Introductionunclassified

“…[1][2][3][4][5][6][7] Klasik ve lateralizan değeri yüksek semiyolojik belirtilerin yanında daha az sıklıkta karşılaşılan ve literatürde laterizasyon açısından tartışmalı belirtiler de gözlenmektedir. [3][4][5][6][7] Özellikle peri-iktal vejetatif semptomlar ile klinik çalışmalar sınırlı sayıdadır ve çoğu olgu düzeyinde bildirimlerdir. [8][9][10][11][12][13][14][15][16] Bu çalışmanın amacı, hasta çalışmamızda klinik nöbet semptomlarının sıklığını saptamak ve klasik lateralizan değeri yüksek bulgular yanında görece nadir görülen bulguların lateralizasyon değerini belirlemektir.…”

Section: Introductionunclassified

See 2 more Smart Citations

Temporal lob epilepsisinde semiyolojinin lateralizasyon değeri

Türe¹

2019

Epilepsi

View full text Add to dashboard Cite

Objectives: This study aims to determine the prevalence of lateralized semiological findings in patients with temporal lobe epilepsy and to assess the contribution of relatively rare symptoms to lateralization, as well as classical lateralizing findings. Methods:The records of the 329 patients who were monitored by video-EEG for evaluation of epilepsy surgery were retrospectively reviewed in this study. The lateralization of the seizures was evaluated with ictal EEG and semiological findings. The records of 128 patients with unilateral temporal lobes were analyzed.Results: In our study, 343 seizures of the 128 patients were analyzed. Aura was identified on 241 patients (70.2%). The presence of aura was not associated with lateralization. Vertigo (p=0.02) and deja vu (p=0.04) indicated right temporal lobe in all seizures. One of the most frequently observed ictal clinical findings was oroalimenter automatism, but its presence was not significant for lateralization. Peri-ictal vegetative symptoms of ictal cough, vomiting, water drinking, hypersalivation and the urinary urge are rarely seen in the right temporal lobe-induced seizures were seen more frequently (p<0.05). Most of the ictal motor findings showed contralateral hemispheres. Clonic jerk ended the ipsilateral focus in all seizures (p=0.004). Conclusion:The presence of peri-ictal vegetative symptoms may help lateralize the epileptic focus to the right hemisphere when evaluated with other classical findings. Analysis of the seizure semiology that involves the phenomenon of lateralized seizures is a significant component of preoperative evaluation.

show abstract

Klinische Lateralisations- und Lokalisationszeichen

Knake

Menzler

2020

Epileptische Anfälle Und Epilepsien Im Erwachsenenalter

View full text Add to dashboard Cite

An evaluation of lateralizing signs in patients with temporal lobe epilepsy

Cited by 13 publications

References 35 publications

Hand posture as localizing sign in adult focal epileptic seizures

Hand posture as localizing sign in adult focal epileptic seizures

Temporal lob epilepsisinde semiyolojinin lateralizasyon değeri

Klinische Lateralisations- und Lokalisationszeichen

Contact Info

Product

Resources

About