An evaluation of pharmacogenomic information provided by five common drug information resources

Vaughan, K.T. L.; Scolaro, Kelly L.; Anksorus, Heidi N.; Roederer, Mary W.

doi:10.3163/1536-5050.102.1.009

Cited by 16 publications

(16 citation statements)

References 24 publications

(17 reference statements)

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“…Overall, Lexicomp better provided pharmacogenomic information for the twenty-seven drugs than the other three resources, consistent with results of a previous study [2]. Lexicomp was the only commercial drug information resource that included a separate pharmacogenomics section.…”

Section: Discussionsupporting

confidence: 88%

“…Pharmacogenomics is the study of how genes affect a person's response to drugs [1]. A study evaluating the presence or absence of pharmacogenomic biomarkers in 5 popular drug information resources showed wide variability, from 68% to 95%, in the inclusion of such information [2]. However, it is unknown whether they provide clinically useful pharmacogenomic information such as biomarker effect, population prevalence, testing recommendations, and interpretation of the test result.…”

mentioning

confidence: 99%

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Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information

Chang¹,

Pham²,

Dang³

et al. 2016

J Med Libr Assoc

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Section: Discussionsupporting

confidence: 88%

mentioning

confidence: 99%

Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information

Chang¹,

Pham²,

Dang³

et al. 2016

J Med Libr Assoc

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“…The first review of EED was undertaken between 1994 and 1999. A particular interest on evidence-based information offers a comprehensive drug database Lexicomp, a full-text access reference guide to point-of-care [19].…”

Section: Integrated Healthcare Getting Research Into Practicementioning

confidence: 99%

Advancing the Direction of Health Information Management in Greek Public Hospitals: Theoretical Directions and Methodological Implications for Sharing Information in order to Obtain Decision-Making

Lappa

2016

Informatics

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Although consultants have long placed the use of research information at the centre of their activity, the extent that physicians use this information tends to vary widely. Despite this study and its recommendations, there is still a gap between the functions of a manager and the use of the associated information, while the decision-making procedures vary according to the organization in which they work. The cost of IT remains the largest barrier, while some current IT solutions are not user friendly and out-of-date, particularly for public hospitals in Greece. The knowledge management is concerned not only with the facts and figures of production, but also with the know-how of staff. The information needs protocol should not be referred only to those who comply with formal computer-based information systems, but also to those who take into account other informal information and its flow within the organization. In a field such as medicine, where out-of-date information may be positively dangerous, doctors make heavy use of journals and several texts from the web. The decision-making process is a complex approach, particularly in human diagnostic and therapeutic applications. Therefore, it is very important to set priorities in the sector of health information management and promote education and training on information and communication technology (ICT).

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“…That information is scattered throughout the label, appearing for different drugs in many different sections. A variety of the widely-used electronic information resources include pharmacogenomic information[26]. However, the information is often incomplete, with resources containing between 50% and 90% of the pharmacogenomics information that is available in FDA approved product labels[26].…”

Section: Introductionmentioning

confidence: 99%

Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements

Romagnoli

Boyce

Empey

et al. 2016

International Journal of Medical Informatics

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Introduction As key experts in supporting medication-decision making, pharmacists are well-positioned to support the incorporation of pharmacogenomics into clinical care. However, there has been little study to date of pharmacists’ information needs regarding pharmacogenomics. Understanding those needs is critical to design information resources that help pharmacists effectively apply pharmacogenomics information. Objectives We sought to understand the pharmacogenomics information needs and resource requirements of pharmacists. Methods We conducted qualitative inquiries with 14 pharmacists representing 6 clinical environments, and used the results of those inquiries to develop a model of pharmacists’ pharmacogenomics information needs and resource requirements. Results The inquiries identified 36 pharmacogenomics-specific and pharmacogenomics-related information needs that fit into four information needs themes: background information, patient information, medication information, and guidance information. The results of the inquiries informed a model of pharmacists’ pharmacogenomics resource requirements, with 3 themes: structure of the resource, perceptions of the resource, and perceptions of the information. Conclusion Responses suggest that pharmacists anticipate an imminently growing role for pharmacogenomics in their practice. Participants value information from trust-worthy resources like FDA product labels, but struggle to find relevant information quickly in labels. Specific information needs include clinically relevant guidance about genotypes, phenotypes, and how to care for their patients with known genotypes. Information resources supporting the goal of incorporating complicated genetic information into medication decision-making goals should be well-designed and trustworthy.

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An evaluation of pharmacogenomic information provided by five common drug information resources

Abstract: Health sciences librarians should be aware of the variation in biomarker availability when recommending drug resources for licensing and use. Librarians can also use this study to encourage publishers to include pharmacogenomics information from the package insert as a minimum standard.

Cited by 16 publications

References 24 publications

Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information

Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information

Advancing the Direction of Health Information Management in Greek Public Hospitals: Theoretical Directions and Methodological Implications for Sharing Information in order to Obtain Decision-Making

Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements

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