An evaluation of polyps detected in 20,847 routine sigmoidoscopic examinations

Wilson, Gerald S.; Dale, Esther H.; Brines, Osborne A.

doi:10.1016/0002-9610(55)90707-8

Cited by 23 publications

(2 citation statements)

References 16 publications

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“…The value of rigid sigmoidoscopy is frequently limited by a failure to pass the instrument to its full length. In 50% of 21,000 examinations in one study, it was impossible to pass the instrument beyond 20 cm [16]. Even when passed to its full extent, the instrument often simply stretched the rectosigmoid region and only a small part of the sigmoid colon was actually seen.…”

Section: Endoscopymentioning

confidence: 99%

Screening for colorectal cancer: A critical review

Hardcastle

Pye

1989

World j. surg.

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This article discusses the place of symptom detection, endoscopy, and fecal occult blood testing in population screening for colorectal cancer. There is now considerable evidence that screening the population over the age of 50 years for occult blood in the feces will result in an increased yield of tumors localized to the bowel at the time of surgical treatment. These tumors also have other favorable prognostic features and it is likely that the prognosis of this group will be better than the prognosis of patients presenting with symptoms in the usual way. Because of the biases that result from the selection and detection of tumors in screening studies, the mortality results of the control trials now underway must be awaited until it is known whether population screening is of real value. In chemical fecal occult blood screening tests, a compromise has to be made between sensitivity and specificity. The fecal occult blood test most widely used and the one that has been subjected to the most evaluation in screening studies is the guaiac-based slide test, Hemoccult. The predictive value of a positive test for invasive cancer is 11-17%, and for adenomas, 36-41%. This specificity is achieved at a loss of sensitivity, the interval cancer rate reported in screening studies being over 20%. Newly developed immunological techniques appear to be more sensitive and specific, but require further evaluation in population screening studies.

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Section: Endoscopymentioning

confidence: 99%

Screening for colorectal cancer: A critical review

Hardcastle

Pye

1989

World j. surg.

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“…Because patients with precancerous lesions of the large bowel have no characteristic symptoms [6,14], sigmoidoscopy has been especially recommended as a supplement to a complete physical examination [13][14][15][16]. Such an approach could ensure detection of 50% of all benign polyps ( Fig.…”

mentioning

confidence: 99%

Reliability of routine double-contrast examination (DCE) of the large bowel in polyp detection: A prospective clinical study

Fork

Lindström

Ekelund

1983

Gastrointest Radiol

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A total of 2,118 consecutive patients, examined with double-contrast examination of the large bowel (DCE), were evaluated radiographically, clinically, and endoscopically for up to 48 months. A total of 402 polyps were diagnosed during the follow-up period. Of these, 307 were revealed at the first DCE and 95 at subsequent endoscopy or autopsy. The accuracy of the DCE for demonstrating or excluding patients with polypoid lesions of the colon was 97%, whereas the predictive value of a positive DCE report was 96% and a negative one, 97%. However, the ability to demonstrate every known polyp at DCE was only 63%, although the probability of a polypoid lesion demonstrated at DCE being a true polyp was 92%.

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Colorectal Polypoid Lesions

Camp¹,

Connolly²

1966

Arch Surg

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An evaluation of polyps detected in 20,847 routine sigmoidoscopic examinations

Cited by 23 publications

References 16 publications

Screening for colorectal cancer: A critical review

Screening for colorectal cancer: A critical review

Reliability of routine double-contrast examination (DCE) of the large bowel in polyp detection: A prospective clinical study

Colorectal Polypoid Lesions

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