An evaluation of the 10-year major osteoporotic and hip facture risk using the FRAX score in Erzurum

Abstract

Aim: The aim of this prospective study was to provide an estimation of the 10-year probability of the four major osteoporotic fractures using fracture risk evaluation scale (FRAX) and to review the risk factors for osteoporosis in males and females aged over 50 years in Erzurum, Turkey. Material and Method: An evaluation was made 1254 patients who presented at the Outpatient Clinics of State Hospital in 2013. Taking the risk factors and bone mineral density (BMD) values into consideration, and using the FRAX risk evaluation scale, the 10-year major osteoporotic (MO) and hip fracture risks were evaluated for all the participants. Results: While a significant difference was seen between the genders in respect of measurements of the osteoporosis (OP) major risk fracture with BMD determined as mean 7.4% in females and 5.77% in males, and without BMD, as 8.27% in females and 4.59% in males and without BMD, the hip fracture risk was 2.92% in females and 1.91% in males (p=0.016, p<0.001, p<0.001, respectively), no significant difference was determined in the hip fracture risk with BMD at 2.62% in females and 3.05% in males (p=0.517). With an increase in body mass index (BMI), there was a decrease in the OP risk (p<0.001). With BMD, the MO fracture risk groups were formed of 84.5% low risk, 10.5% moderate risk and 5% high risk. Discussion: If BMD values were taken as the basis for medical treatment in Turkey, the use of scanning tests and fracture risk evaluation scales such as FRAX would be useful. However, to be able to better determine the extent of OP and the fracture risk in the general population and maybe to be able to determine threshold values which may be different in our population, there is a need for further multi-center studies including greater numbers of patients. Early diagnosis of OP, identification of risk groups for early treatment and prevention, and determination of the risk before a fracture all play an important role in the prevention of morbidity and mortality associated with OP and in the reduction of healthcare costs. Therefore, the aim of this study was to determine cases of osteopenia and OP in the early stages by measuring BMD and to determine the 10-year fracture risk using the FRAX scale in patients presenting at our hospital. Keywords Material and MethodIn the study period of 2013, a total of 1254 patients aged over 50 years, with no previous OP treatment underwent a DEXA scan at State Hospital. BMD measurements were taken with a DEXA Hologic Q 2000 device of the posteroanterior lumbar spine (L1-L4) and hip (femoral neck). The machine calibrations, tests, controls, and phantom measurements were applied routinely by certified technicians. The participants removed outer clothing and were weighed and measured, then DEXA scanning was applied. The BMD values were evaluated with the T-scores defined according to the peak young adult bone density value. According to the WHO classification, patients with a T-score of ≤-2.5 were accepted as osteoporotic, those with scores of -1--2.5 as os...

Alanya ve Yöresi Türk Toplumu Kadınlarında Kemik Mineral Yoğunluğu Değerleri: Kesitsel Karşılaştırmalı çalışma

“…In these devices, white race (Caucasian) standardization data is usually used. Some studies have been carried out on the BMD values of Turkish society in various regions of our country [1][2][3][4][5][6][7].…”