An evaluation of the diagnosis and treatment of chordoma

Unusual Subarachnoid Metastasis of an Intracranial Chordoma in Infancy

“…The rarity of this neoplasm was pointed out by G hntil and C oley [10], M abrey [ 16], Sassen and C hutorian [20] and F orti [7], According to Mabrey [16|, G ardner and T urner [9] and Kamrin et al [14], 48-55% of all chordomas have a sacrococcygeal localization. 25-30°/o are intracranial and 10-25% in the spine, but recent reports in dicate that they are just as common inside the cranium as in the sacrococ cygeal region [8,11,21], Intracranial chordomas are more frequent in the 3rd and 4th decades of life, while the sacrococcygeal localization predominates in the 5th and 6th decades [1,2,6,11,12], They are very rare in infancy and childhood [3,20], Chordomas are benign neoplasm and characteristically show a slow growth with metastatic potential.…”

Primary Malignant Bone Tumours: A Retrospective Study of 869 Cases Reported to the Finnish Cancer Registry between 1962 and 1968

“…Radical excision of a spheno-occipital tumour is seldom possible. Tumours in ,this area easily cause lethal pressure in the region of 'the medulla oblongeta, It is quite often possible to remove a sacrococcygeal chordoma by radical surgery and then the prognosis is good (Kamrin et al 1964, Rissanen et al 1967, Paavolainen et al 1976). …”

Chordoma of the Thoracic Spine. Case Report.

“…5,8,18,19,24,26,31,37) Chordomas of the mobile spine metastasize more often than sacrococcygeal lesions, 18) to the skin, lung, lymph node, bone, liver, and other intraabdominal viscera. 3,8,9,18,21,25,31,37) Intradural metastasis 21) and subarachnoid dissemination 1) may also occur.…”

“…2,3,11,17) However, almost all cases in the sphenooccipital and cervical regions occur in the first two decades of life. 9,12,19,34) Vertebral chordomas tend to occur in somewhat younger populations and frequently are more aggressive. 18,26,31) Chordomas affect men more then women at a ratio of 2.7/1 to 1.6/1.…”

“…12,18,19,26,31,32,34) Thoracic involvement is 2-5%. 29,31,32,34) Extraosseous chordoma may occur within the sella, paranasal sinuses, larynx, maxilla, and nasopharynx 7) or scapula, 18) as well as ectopic intradural foci in the pons and spinal canal.…”