Food safety is critical to avoid side effects arising from contamination in protecting public health. Hygiene and sanitation knowledge and practice are factors influencing food safety performance. Meanwhile, food hygiene and sanitation are still an issue for some of the street vended food that need to investigate further. This study aims to present an overview of street food vendors’ sanitation and hygiene. This systematic review used the PRISMA guidelines as its methodology. Using databases including EBSCOHOST, Scopus, Taylor & Francis, Wiley Online, and PubMed, relevant and related studies were found. Food hygiene, food sanitation, street food vendors, and handlers of street food represent the keywords for the identification procedure. Only 18 of the 3022 publications that were identified from such databases were included in the final paper criteria.