An evaluation of the infection agents and the demographic characteristics of patients followed up on a mechanical ventilator in neurology intensive care: A retrospective, single center, observational study

Abstract

How to cite / Atıf için: İnanç Y, İnanç Y. An evaluation of the infection agents and the demographic characteristics of patients followed up on a mechanical ventilator in neurology intensive care: A retrospective, single center, observational study.This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND 4.0) where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. AbstractAim: The incidence of nosocomial infections is higher than other sites of the hospitals at intensive care units (ICU) because of high frequency of invasive interventions and multidrug resistant microorganism's prevalence. Ventilator-related pneumonia cases have the highest mortality risk among the nosocomial infections. The aim of this study was to evaluate the endotracheal aspirate cultures and the demographic characteristics of patients followed up on mechanical ventilation in Neurology Intensive Care. Methods: Our study was designed as a retrospective, cross-sectional and descriptive. Retrospective evaluation was made of 51 patients who were attached to a mechanical ventilator in the last 6 months and from whom a tracheal aspirate culture was taken.The endotracheal aspirate samples were taken under sterile conditions using a specifically designed catheter with the method of administering saline into the intubation tube and then aspiration. Blood culture results sent for analysis at the same time as the tracheal aspirate samples were also retrospectively evaluated in patients determined with positive production. A record was made of the demographic characteristics of the patients, diagnosis on admittance to ICU, risk factors, and microbial production in the tracheal aspirate culture. Results: In the first culture, there was no production in 22 (43.1%) cases, and Acinetobacter baumanii was determined in 14 (27.5%) patients, Pseudomonas aeruginosa in 3 (5.9%), Klebsiella pneumonia in 3 (5.9%), Staphylococcus aureus in 2 (3.9%), Corynebacterium striatum in 2 (3.9%), Acinetobacter baumanii + Pseudomonas aeruginosa in 2 (3.9%), Acinetobacter baumanii + Klebsiella pneumonia in 2 (3.9%), and Acinetobacter baumanii + Escherichia coli in 1 (2.0%). The second culture was taken from patients on the mean 11th day. In 3 (10.7%) patients there was no production in the second culture and in the other patients, Acinetobacter baumanii was determined in 15 (53.6%) patients, Pseudomonas aeruginosa in 3 (10.7%), Klebsiella pneumonia in 2 (7.1%), Escherichia coli in 1 (3.6%), Corynebacterium striatum in 1 (3.6%), and Acinetobacter baumanii + Pseudomonas aeruginosa in 3 (10.7%). Conclusion: The culture results in this study of patients admitted for neurological reasons were observed to be consistent with findings in literature. The high mortality rate of 64.7% in these ICU patients is due to the majority being ischemic stroke patients. This sugge...

Thrombocytopenia and its effect on mortality and morbidity in the intensive care unit

“…In our study, the rate of thrombocytopenia in the ICU was 30%, which was similar to the previous studies [14][15][16][17]. In the study of Singh et al, the rates of patients with thrombocyte count below 100,000 / uL varied between 20-40% [13]. In the studies conducted by Knöbl et al [17] and Hanes et al [18] the rates of those with a thrombocyte level below 100.000 /uL and 50.000 /uL were between 20-25% and 12-15%, respectively.…”

“…In numerous studies, thrombocytopenia rates in the ICU varies between 35-45% and approximately half of these patients developed thrombocytopenia during intensive care hospitalization [9,10]. In the studies of Provan et al and Strauss et al, this rate was between 35% and 44%, and in the study conducted by Singh et al, thrombocytopenia rate was between 20-40% [11][12][13]. In our study, the rate of thrombocytopenia in the ICU was 30%, which was similar to the previous studies [14][15][16][17].…”

The effect of different concentrations of chlorhexidine on microbial colonization: A double‐blinded randomized controlled study

“…VAP is the second most common nosocomial infection seen in intensive care units, with an incidence reported in the literature of between 2.5% and 75.3% (Chen et al, 2016; Haghighi et al, 2017; Jansson & Syrja, 2019; Kanafani et al, 2019; Khan et al, 2017; Kollef et al, 2012; Öcal et al, 2016; Thakuria et al, 2013; Werarak et al, 2010; Zand et al, 2017). It is reported that the microorganism species P. aeruginosa , S. aureus , Acinetobacter baumannii and E. coli are frequently seen in patients under mechanical ventilation (Eren et al, 2017; İnanç & İnanç, 2018; Şahin et al, 2019). According to the research findings, very different species of microorganisms were found to reproduce in the four groups of patients.…”

Bir Üniversite Hastanesi Noroloji Yoğun Bakım Ünitesinde Gelişen Enfeksiyonların Değerlendirilmesi

“…[26,27] Yapılan çalışmalarda pnömoni etkeni patojenlerin sıklık sırasına göre Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus olduğu gösterilmiştir. [1,28] [1] En sık etken olarak koagülaz negatif stafilokoklar (KNS) ve S. aureus bildirilmiştir. [12,13] Enfeksiyon SVK'ın kullanımının herhangi bir döneminde meydana gelebilir.…”