An evaluation of the SMA 12/Micro AutoAnalyzer in the clinical biochemistry laboratory

Logan, R. W.; Tweedie, Anne

doi:10.1016/0009-8981(73)90162-9

Cited by 8 publications

(2 citation statements)

References 2 publications

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“…Determination of plasma calcium, phosphorus, and protein was accomplished using an SMA 12 Micro AutoAnalyser as described by Logan and Tweedie (1973). Plasma magnesium was determined by atomic absorption spectrophotometry according to the method of Stewart, Hutchinson, and Fleming (1963), and blood glucose was measured using a Beckmaa glucose analyser.…”

Section: Methodsmentioning

confidence: 99%

Calcium, phosphorus, and magnesium concentrations in plasma during first week of life and their relation to type of milk feed.

Lealman¹,

Logan²,

Hutchison³

et al. 1976

Archives of Disease in Childhood

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. (1976). Archives of Disease in Childhood, 51, 377. Calcium, phosphorus, and magnesium concentrations in plasma during first week of life and their relation to type of milk feed. Serial changes in plasma levels of calcium, phosphorus, magnesium, alkaline phosphatase, and total proteins have been investigated in 138 healthy, term Caucasian infants. Blood samples were obtained for each infant from cord blood and on day 1 and day 6. The infants were studied in three groups according to whether they were breast fed, received 'Ostermilk No. 1' or 'Cow and Gate V' formulas.Levels of calcium, phosphorus, magnesium, alkaline phosphatase, and total proteins did not differ between the groups at birth or on day 1. By day 6 calcium levels were higher and phosphorus levels lower in the breast-fed infants compared with either of the artificially-fed groups. Phosphorus levels were lower in the V Formula group compared with the Ostermilk group but the mean calcium levels of these two groups did not differ significantly. However, only 2 * 8 % of the V Formula group developed hypocalcaemia compared with 18 2% of the Ostermilk group. The only infant developing clinical tetany belonged to the group fed Ostermilk. Evidence is also given which suggests that those infants with low calcium levels on day 1 who were fed the high-solute milk tended to show a fall in calcium by day 6. This did not apply to the two other groups. It is concluded that the use of adapted cows' milk preparations for infant feeding should lead to a reduction in the incidence of neonatal tetany.

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Section: Methodsmentioning

confidence: 99%

Calcium, phosphorus, and magnesium concentrations in plasma during first week of life and their relation to type of milk feed.

Lealman¹,

Logan²,

Hutchison³

et al. 1976

Archives of Disease in Childhood

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“…1 and Trophysan 5 was measured on more than one occasion to ensure that the values published by the manufacturers could be taken as accurate in subsequent calculations. Plasma electrolytes, calcium, phosphorus, and liver function tests were determined using a Technicon SMA 12/Micro Auto-Analyzer as described by Logan and Tweedie (1973), and determination of acid-base status by means of Radiometer (Astrup) equipment. Urinary total free a amino nitrogen excretion was analysed by the method of Rubinstein and Pryce (1959), and plasma and urinary amino acids were measured after deproteinization of 1 ml samples with 200 mg salicylsulphonic acid, by means of a Technicon TSM I amino acid analyser.…”

Section: Methodsmentioning

confidence: 99%

Comparison of an oral and an intravenous feeding regimen in the newborn

Logan¹,

Young²,

Ross³

et al. 1974

Archives of Disease in Childhood

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(1974). Archives ofDisease in Childhood, 49,200. Comparison of an oral and an intravenous feeding regimen in the newborn. In a series of neonates undergoing comparable operations which did not affect the alimentary tract, the relative merits of similar oral and intravenous feeding regimens were compared. Metabolic balance studies were performed, together with measurement of plasma and urinary amino acids. Though the clinical response to both regimens was satisfactory, it was found that, in the group fed intravenously, certain of the plasma and urinary amino acids attained concentrations outside normal limits. This was almost certainly due to the nature of the amino acid solution infused.With the development of numerous solutions of amino acids, carbohydrate, and fat suitable for intravenous infusion, the ability to sustain life by the administration of these solutions has become feasible (Wilmore et al., 1969). The value of intravenous feeding in the newborn, who has undergone operation which precludes feeding by the alimentary tract, has been shown to be life-saving (Asch, Huxtable, and Hays, 1972), but the value of intravenous feeding in the postoperative phase has yet to be defined (Johnston, Tweedle, and Spivey, 1972). Doubt exists about the utilization of solutions administered intravenously (Jarnum et al., 1969;Larsen and Brockner, 1969), and it is important to determine if intravenous feeding will produce a better anabolic response after operation as compared with that achieved by the gradual reintroduction of oral feeding.This study was performed in a series of infants undergoing comparable operations which did not affect the alimentary tract. Two groups are compared, one with an oral diet and the other with an intravenous feeding regimen yielding comparable fluid, calorie, mineral, and vitamin intakes. Balance studies were made on these patients. Subjects and methodsPatients admitted in the first 24 hours of life on account of meningocele or myelomeningocele, in whom early operation was indicated, were selected. The

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