An Evaluation of the Work and Life Conditions and the Quality of Life in 60 to 65 Year-Old White-Collar Employees, Manual Workers, and Unemployed Controls

Sołtysik, Bartłomiej K.; Kroc, Łukasz; Pigłowska, Małgorzata; Guligowska, Agnieszka; Śmigielski, Janusz; Kostka, Tomasz

doi:10.1097/jom.0000000000001029

Cited by 12 publications

(11 citation statements)

References 17 publications

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“…Another study using panel data also reported that people engaged in paid work during old age had a high quality of life [38]. However, the quality of life of older adults who engaged in physical labor was lower than that of office workers and was more affected by health factors than that of office workers [39]. Korea has a higher employment rate for older adults than European Union (EU) countries [40], and while the employment rate of the 65-to 69-year-old age group in Korea is higher than that of the OECD average, most of the older adults in Korea finish their core careers in thier early 50s and tend to obtain low-quality and unstable jobs [3].…”

Section: Discussionmentioning

confidence: 99%

Relationship between Active Aging and Quality of Life in Middle-Aged and Older Koreans: Analysis of the 2013–2018 KNHANES

Eum

Kim

2021

Healthcare

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With the increase in the aging population worldwide, social interest in having a vibrant and valuable old age has been increasing with changes in the perspectives on old age. This study aimed to determine the relationship between active aging and health-related quality of life (HRQOL) in middle-aged and older Korean using national data. The subjects were 14,117 adults aged ≥55 years. HRQOL was evaluated using the EuroQol–5 Dimension (EQ-5D) questionnaire, and active aging was defined based on the health factors, participation factors, and security factors. The average EQ-5D score was 91.04 ± 0.143. Hierarchical multiple regression analysis sequentially inputting the health, participation, and security factors showed that health factors had the strongest influence on HRQOL (F = 216.656, p < 0.001). In the final model, which included all variables, activity limit (B = −10.477, p < 0.001) and subjective health status (B= −7.282, p < 0.001) were closely related to the HRQOL. In addition, economic activity, income level, home ownership, private health insurance, and unmet healthcare needs were associated with HRQOL. The R2 of the model was 38.2%. To improve the HRQOL of middle-aged and older people, it is necessary to consider active aging factors. Furthermore, follow-up studies using various indicators reflecting active aging should be conducted.

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Section: Discussionmentioning

confidence: 99%

Relationship between Active Aging and Quality of Life in Middle-Aged and Older Koreans: Analysis of the 2013–2018 KNHANES

Eum

Kim

2021

Healthcare

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“…Our present study presents the results obtained in subgroups of volunteers participating in the project entitled “The occurrence of oxidative stress and selected risk factors for cardiovascular risk and functional efficiency of older people in the context of workload” (funded by the Central Institute For Labour Protection-National Research Institute, Warsaw, Poland, and supervised by the Clinic of Geriatrics at Medical University in Lodz, Poland). Two basic inclusion criteria were ages within the range of 60 to 65 years and the willingness to participate [29]. To ensure approximately equal participation of men and women, a stratified probability sampling algorithm was used.…”

Section: Methodsmentioning

confidence: 99%

Platelet and Red Blood Cell Counts, as well as the Concentrations of Uric Acid, but Not Homocysteinaemia or Oxidative Stress, Contribute Mostly to Platelet Reactivity in Older Adults

Karolczak

Sołtysik

Kostka

et al. 2019

Oxidative Medicine and Cellular Longevity

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Purpose The goal of this study was to estimate the hierarchical contribution of the most commonly recognized cardiovascular risk factors associated with atherogenesis to activation and reactivity of blood platelets in a group of men and women at ages 60-65. Methods Socioeconomic and anthropometric data were taken from questionnaires. Blood morphology and biochemistry were measured with standard diagnostic methods. Plasma serum homocysteine was measured by immunochemical method. Plasma concentrations of VCAM, ICAM, total antioxidant status, and total oxidant status were estimated with commercial ELISA kits. Markers of oxidative stress of plasma and platelet proteins (concentrations of protein free thiol and amino groups) and lipids (concentrations of lipid peroxides) and generation of superoxide anion by platelets were measured with colorimetric methods. Platelet reactivity was estimated by impedance aggregometry with arachidonate, collagen, and ADP as agonists. Expression of selectin-P and GPIIb/IIIa on blood platelets was tested by flow cytometry. Results Platelet aggregation associated significantly negatively with HGB and age and significantly positively with PLT, MPV, PCT, PDW, and P-LCR. When platelet reactivity (“cumulative platelet reactivity_aggregation”) was analyzed in a cumulated manner, the negative association with serum concentration of uric acid (Rs = −0.169, p = 0.003) was confirmed. Multivariate analysis revealed that amongst blood morphological parameters, platelet count, plateletcrit, and number of large platelets and uric acid are the most predictive variables for platelet reactivity. Conclusions The most significant contributors to platelet reactivity in older subjects are platelet morphology, plasma uricaemia, and erythrocyte morphology.

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“…Two basic inclusion criteria were: age within the range of 60 to 65 years and the willingness to participate. The recruitment criteria are described in more detail in an earlier report [ 50 ]. To ensure approximately equal participation of men and women, a stratified probability sampling algorithm was used.…”

Section: Methodsmentioning

confidence: 99%

Testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women

Karolczak

Konieczna

Kostka

et al. 2018

Aging

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The cardiovascular effects of testosterone and dihydrotestosterone are generally attributed to their modulatory action on lipid and glucose metabolism. However, no ex vivo studies suggest that circulating androgen levels influence the activation and reactivity of blood platelets – one of the main components of the haemostasis system directly involved in atherosclerosis. The levels of testosterone, dihydrotestosterone and oestradiol in plasma from men and women aged from 60 to 65 years were measured by LC-MS; the aim was to identify any potential relationships between sex steroid levels and the markers of platelet activation (surface membrane expression of GPII/IIIa complex and P-selectin) and platelet reactivity in response to arachidonate, collagen or ADP, monitored with whole blood aggregometry and flow cytometry. The results of the ex vivo part of the study indicate that the concentrations of testosterone and its reduced form, dihydrotestosterone are significantly negatively associated with platelet activation and reactivity. These observations were confirmed in an in vitro model: testosterone and dihydrotestosterone significantly inhibited platelet aggregation triggered by arachidonate or collagen. Our findings indicate that testosterone and dihydrotestosterone are significant haemostatic steroids with inhibitory action on blood platelets in older people.

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An Evaluation of the Work and Life Conditions and the Quality of Life in 60 to 65 Year-Old White-Collar Employees, Manual Workers, and Unemployed Controls

Abstract: Quality of work and health assessment are the main domains that influence older workers' QoL and may contribute to the shortening of the work period and accelerated transfer to retirement. Quality of work assessment seems especially important in older manual workers.

Cited by 12 publications

References 17 publications

Relationship between Active Aging and Quality of Life in Middle-Aged and Older Koreans: Analysis of the 2013–2018 KNHANES

Relationship between Active Aging and Quality of Life in Middle-Aged and Older Koreans: Analysis of the 2013–2018 KNHANES

Platelet and Red Blood Cell Counts, as well as the Concentrations of Uric Acid, but Not Homocysteinaemia or Oxidative Stress, Contribute Mostly to Platelet Reactivity in Older Adults

Testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women

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