An evaluation of two new haemagglutination tests for the rapid diagnosis of autoimmune thyroid diseases.

Abstract

SUMMARY Two haemagglutination tests using preserved turkey erythrocytes are described for the detection of thyroglobulin and microsomal antibodies, respectively. Comparative studies with the more traditional sheep cell techniques show good correlation of titres when testing sera from patients with autoimmune thyroid disorders.

Alopecia Areata and Associated Diseases in Saudi Patients

“…The figure of 5.4% in our patients with antithyroid antibodies does not differ significantly from that observed for the control group (3.4%), and is in accordance with that reported for the normal population studies conducted in other parts of the world [31,32]. Moreover, the titers of positive tests were similar to those observed in the normal population, i.e., < 1:20 for antithyroglobulin antibody and < 1:400 for antimicrosomal antibody [31].…”

The impact of metabolic syndrome on insulin sensitivity, glucose sensitivity, and acute insulin response after glucose load in early-onset type 2 diabetes mellitus: Taiwan Early-Onset Type 2 Diabetes Cohort Study

“…Antimicrosomal antibody and anti-thyroglobulin antibody were semiquantified by the Boyden passive hemagglutination (HA) system (Thymune*-M and Thymune-T*, respectively; Abbott, Dartford, United Kingdom) [16]. The correlation between HA and fluorescent antibody titer was also found to be good, showing a linear relationship between titers of up to 1/1 600 000 for the HA test and 1/1280 for the fluorescent antibody titer test [17].…”

A case of untreated chronic goitrous autoimmune thyroiditis with spontaneous fluctuation between different metabolic levels

“…Antibodies against thyroidal microsomal antigens (MsA) were in 1980 detected by indirect immunofluorescence and in 1981-83 by indirect haemagglutination techniques. Circulating thyroglobulin antibodies (TgA) were detected by hae¬ magglutination techniques (Kornstad & Kornstad 1964), modified according to Cayzer et al (1978). Thyrotrophin-binding inhibiting immunoglobulins (TBII) were determined by the radioreceptorassay described by Wägar et al (1982).…”