2015
DOI: 10.1016/s2215-0366(15)00156-x
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An evidence map of psychosocial interventions for the earliest stages of bipolar disorder

Abstract: Depression, schizophrenia, and bipolar disorder are three of the four most burdensome problems in people aged under 25 years. In psychosis and depression, psychological interventions are effective, low-risk, and high-benefit approaches for patients at high risk of first-episode or early-onset disorders. We review the use of psychological interventions for early-stage bipolar disorder in patients aged 15–25 years. Because previous systematic reviews had struggled to identify information about this emerging sphe… Show more

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Cited by 92 publications
(75 citation statements)
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“…Although pharmacotherapy is the treatment of choice for serious mental illness, there are clinical recommendations that suggest, especially at the first onset of symptoms, that psychotherapy can be very effective 40,41 . Our data suggest this is an opportunity for improving services for these patients.…”
Section: Discussionmentioning
confidence: 99%
“…Although pharmacotherapy is the treatment of choice for serious mental illness, there are clinical recommendations that suggest, especially at the first onset of symptoms, that psychotherapy can be very effective 40,41 . Our data suggest this is an opportunity for improving services for these patients.…”
Section: Discussionmentioning
confidence: 99%
“…Second, we suggest that it would be feasible and justifiable to monitor depressed youth at risk of ET-BD for this time period to offer the prospect of early interventions as appropriate 40 .…”
Section: Discussionmentioning
confidence: 99%
“…This would seem to indicate that it may be possible to develop a combined tool that could not only further our understanding not only of who is at risk of ET-BD, but also identify if any characteristics are unique to a 'mood disorder trajectory' and which may be shared with individuals who make a transition to psychosis. Clinically, this may help to plan generic as well as specific interventions and treatments 40 . It would also provide opportunities for research into underlying pathophysiological mechanisms associated with transition 6,35,37 .…”
Section: Discussionmentioning
confidence: 99%
“…Not only were there markedly fewer relapses initially over the first 2 years in the specialty clinic group, but these differences persisted and were magnified over the subsequent 4 years even though all patients had returned to TAU after 2 years. These data together with a large number of controlled studies showing superior effects of randomized psychotherapy/psycho-education compared to TAU in children and adults with bipolar disorder [32][33][34], provide strong evidence for the benefits of multi-modal psychotherapeutic and pharmacological treatment.…”
Section: Evidence Of Effectiveness Of Early Interventionmentioning
confidence: 84%