Abstract. The paper shows wind shear impact on PM10 vertical profiles, in Kraków, southern Poland. The data used consist of background data for two cold seasons (Sep. 2018 to Apr. 2019, and Sep. 2019 to Apr. 2020), and data for several case studies from November 2019 to March 2020. The data is composed of PM10 measurements, model data, and wind speed and direction data. The background model data come from operational forecast results of AROME model. PM10 concentration in the vertical profile was measured with a sightseeing balloon. Significant spatial variability of wind field was found. The case studies represent the conditions with much lower wind speed and a much higher PM10 levels than the seasonal average. The inversions were much more frequent than on average, too. Wind shear turned out to be the most important factor in terms of PM10 vertical profile modification. It is generated due to the relief impact, i.e. the presence of a large valley, blocked on one side with the hills. The analysis of PM10 profiles from all flights allows to distinguish three vertical zones of potential air pollution hazard within the valley (about 100 m deep) and the city of Kraków: 1. up to about 60 m a.g.l. – the zone where during periods of low wind speed, air pollution is potentially the highest and the duration of such high levels is the longest, i.e. the zone with the worst aerosanitary conditions; 2. about 60–100 m a.g.l. – transitional zone where the large decrease of PM10 levels with height is observed; 3. above 100–120 m a.g.l. – the zone where air quality is significantly better than in the zone 1, either due to the increase of the wind speed, or due to the wind direction change and advection of different, clean air masses.