2017
DOI: 10.1186/s40795-017-0184-9
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An examination of whether associations exist between maternal and neonatal 25OHD and infant size and adiposity at birth, 6–9 months and 2–2.5 years of age – a longitudinal observational study from the ROLO study

Abstract: Background: Vitamin D status in pregnancy and offspring bone health effects are well established, yet limited knowledge exists on the effect of maternal vitamin D status on offspring size/adiposity. This study examines the association of early (13 weeks), late (28 weeks) pregnancy and neonatal (umbilical) 25-hydroxyvitamin D (25OHD) on offspring size/adiposity.

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“…Neonatal vitamin D concentration also contributes toward the adipocyte cell development of infant body and has inverse relationship: greater the concentration, lower will be the adipogenesis (Horan et al, 2017). At genetic level, maternal vitamin D insufficiency is found to foster genetic mutation in nonobese neonates, and can alter the genes associated with adipose tissue development (Belenchia et al, 2018).…”
Section: Maternal Vitamin D Deficiency and Its Effects On Fetal Healthmentioning
confidence: 99%
“…Neonatal vitamin D concentration also contributes toward the adipocyte cell development of infant body and has inverse relationship: greater the concentration, lower will be the adipogenesis (Horan et al, 2017). At genetic level, maternal vitamin D insufficiency is found to foster genetic mutation in nonobese neonates, and can alter the genes associated with adipose tissue development (Belenchia et al, 2018).…”
Section: Maternal Vitamin D Deficiency and Its Effects On Fetal Healthmentioning
confidence: 99%