An example of axial selectivity in nucleophilic additions to cyclohexanones and cyclohexenones

Abstract

Supplementary Material Available:Tables of positional parameters, thermal parameters, interatomic distances, interatomic angles, and dihedral angles for non-hydrogen atoms (7 pages). Ordering information is given on any current masthead page.(7) Electron-withdrawing groups are known to increase the dipolarophilicity of carbonyl groups toward carbonyl oxides. See ref 2.

Inductive and Resonance Effects of Substituents on π-Face Selection

“…However, the large dependence of π-face selectivity on the properties of the solvent is observed only in the case of ester enolates. Thus, the results of alkylation with those enolates are listed separately for the solvating and nonsolvating media, taking this change in solvent properties as equivalent to lowering enolate basicity. − ,− …”

An investigation into the use of silica-supported bases within EOF-based flow reactors

“…13 C NMR of 2-cyano-3-phenyl acrylic acid ethyl ester 2 synthesised using a micro fabricated device. reduced in order to obtain comparable flow rates.…”

Highly reduced organometallics. 19. Synthesis of carbonyl anions of titanium(0) from titanocene dicarbonyl. The first structural characterization of a carbonyl hydride of titanium

“…An X-ray structural characterization of the hydride revealed a unit cell containing two independent molecules of very similar structures.16 One of these is shown in Figure 1 along with selected interatomic distances and angles. The terminal hydride (Ti-H (av) = 1.75 (7) Á) resides nearly trans to the ring centroid in both molecules. On the basis that the Cp group occupies one coordination site, the titanium is approximately octahedral.…”