This chapter reports the growing body of literature on crime and safety in rural areas via a systematic review of four decades of publications, from 1980 to 2020. This chapter describes the review approach, which focused on English-language literature (in Scopus, JSTOR, and ScienceDirect) in the form of articles, books, and book chapters, and identified research themes. This chapter characterizes the research on crime and safety in rural areas; highlights some of the most prevalent themes, such as policing, crime prevention, and methodology; and emphasizes the importance of the interdisciplinary nature of the field.