2009
DOI: 10.1016/j.chroma.2008.12.070
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An experimental design approach employing artificial neural networks for the determination of potential endocrine disruptors in food using matrix solid-phase dispersion

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Cited by 35 publications
(19 citation statements)
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“…Experimental design was carried out by applying Response Surface Methodology (RSM), widely used for process optimization [36][37][38][39][40][41][42]. This methodology allows optimization of analytical methods by carrying out a relatively small number of experiments and with no prior knowledge of interaction forces between analytes and stationary phase [43][44][45].…”
Section: Data Treatment and Experimental Designmentioning
confidence: 99%
“…Experimental design was carried out by applying Response Surface Methodology (RSM), widely used for process optimization [36][37][38][39][40][41][42]. This methodology allows optimization of analytical methods by carrying out a relatively small number of experiments and with no prior knowledge of interaction forces between analytes and stationary phase [43][44][45].…”
Section: Data Treatment and Experimental Designmentioning
confidence: 99%
“…On the other hand, ANNs are computational model programs which can approximate complex nonlinear relationships existing between independent (ANN input) and dependent (ANN output) variables to an arbitrary degree of accuracy [37]. These relationships are achieved through learning (or training) of data network.…”
Section: Experimental Design Modeling Optimization By Response Surfmentioning
confidence: 99%
“…MSPD presents a reduced consumption of organic solvents, provides high extraction yields and offers a considerable degree of selectivity. MSPD method comprises sample homogenization, cellular disruption, fractionation, and purification in a single process [44]. There are few papers about using MSPD to extract hormones in fatty foods.…”
Section: Introductionmentioning
confidence: 99%