The results of numerical and experimental works dealing with the behavior of gas flow through microchannels are by no means univocal, sometimes agreeing with the classical correlations and other times contradicting them. It is now agreed upon that the effects due to both rarefaction and compressibility must be accounted for. In addition, the experimental works have demonstrated that sometimes compressibility and rarefaction effects can be coupled in microchannels: because these two actions contrast each other, the scatter of the friction factor data for gaseous flows is remarkably large. This paper is aimed