Film cooling and heat transfer measurements were carried out on a cooled nozzle guide vane in a linear cascade, using a transient liquid crystal technique. Three flow conditions were realized : the nominal operating condition of the vane with an exit Reynolds number of 1.47e6, as well as two lower flow conditions: Re 2L =1.0e6 and 7.5e5. The vane model was equipped with a single row of inclined round film cooling holes with compound angle orientation on the suction side. Blowing ratios ranging form 0.3 to 1.5 were covered, all using foreign gas injection (CO 2 ) yielding an engine-representative density ratio of 1.6. Two distinct states of the incoming boundary layer onto the injection station were compared, an undisturbed laminar boundary layer as it forms naturally on the suction side, and a fully turbulent boundary layer which was triggered with a trip wire upstream of injection. The aerodynamic flow field is characterized in terms of profile Mach number distribution, and the associated heat transfer coefficients around the uncooled airfoil are presented. Both detailed and spanwise averaged results of film cooling effectiveness and heat transfer coefficients are shown on the suction side, which indicate considerable influence of the state of the incoming boundary layer on the performance of a film cooling row. The influence of the mainstream flow condition on the film cooling behavior at constant blowing ratio is discussed for three chosen injection regimes.