Aims. Two irradiation experiments on interstellar ice analogs at 80 K under interstellar-like conditions were performed with the LURE SU5 synchrotron beamline to assess, for the first time, the photochemical effect of circularly polarized ultraviolet light (UV CPL) at 167 nm (7.45 eV) with right and left polarizations on such ice mixtures. Methods. This effect was measured by determining the enantiomeric excesses (e.e.s) for two amino acids formed in the solid organic residues produced during the subsequent warm-up of the irradiated samples to room temperature: alanine, the most abundant chiral proteinaceous amino acid produced (both polarizations) and 2,3-diaminopropanoic acid (DAP), a non-proteinaceous amino acid (rightpolarization experiment). These excesses were compared to those measured for the same amino acids produced after unpolarized UV irradiation of the same ice mixtures (expected to be zero), in order to determine the contribution of CPL only. A careful estimate of all the associated uncertainties (statistical and systematic errors) was also developed.Results. It appears that the enantiomeric photochemical effect at this wavelength is weak, since both alanine and DAP e.e.s were found to be small, at most of the order of 1% in absolute values, and tends to be inconclusive since the effects obtained for both amino acids and both polarizations are not those expected. In light of these results, the hypothesis that CPL may be one source responsible for the e.e.s measured for such amino acids in some meteorites and, more generally, that CPL may be directly related to the origin of biomolecular homochirality on Earth is discussed.