An Extensive Morphological and Comparative Study of Clinically Early and Obvious Squamous Cell Carcinoma of the Esophagus

Dépistage du cancer épidermoïde de l’œsophage par endoscopie chez les sujets à risque élevé de cancer

“…Il existe peu de données, mais quelques cas cliniques de diverticules de Zencker dégénérés. Dans une cohorte de plus de 220 000 femmes traitées par radiothérapie pour un cancer du sein, le risque relatif était de 5,42 (IC 95 % : [2,68]) pour le cancer épidermoïde et de 4,22 (IC : [0,25]) pour l'adénocarcinome, dix ans ou plus après la radiothérapie à l'exclusion de tout autre risque de cancer [42].…”

ACP Best Practice No. 155.Guidelines for handling oesophageal biopsies and resection specimens and their reporting

“…Abnormal background mucosa should be adequately sampled. If no obvious tumour is seen on macroscopic examination of oesophagectomy specimens carried out following a diagnosis of in situ squamous carcinoma or high grade dysplasia/ carcinoma in Barrett's mucosa, the entire segment of oesophagus lined by abnormal mucosa should be serially sectioned in longitudinal bands 20 (fig 1D). Before sectioning the specimen, the demonstration of squamous dysplasia/in situ squamous carcinoma may be facilitated by the application of Lugol's solution to the oesophageal mucosa, at a concentration of 1% for one to two minutes and observing the colour change 16 (normal squamous epithelium stains dark brown while severe dysplasia/in situ carcinoma shows no colour change).…”

Prevention and therapy of squamous cell carcinoma of the rodent esophagus using freeze-dried black raspberries

“…Esophageal SCC develops through a progressive sequence from mild to severe dysplasia, carcinoma in situ and, finally, invasive carcinoma [2,3] . This cancer shows marked variation in geographical distribution, with high frequencies in parts of China, Iran, South Africa, Uruguay, France, Italy and Puerto Rico [4] .…”